# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2203701 | [18F]-ST889 | Kd | = | 0.34 | nM | ALA2209374 | 9.47 | nM | Rattus norvegicus | ||
2. | ALA2203701 | [18F]-ST889 | pKd | = | 9.47 | ALA2209374 | 9.47 | nM | Rattus norvegicus | |||
3. | ALA2203701 | [18F]-ST889 | Ratio | = | 40 | ALA2209378 | Rattus norvegicus | |||||
4. | ALA2203701 | [18F]-ST889 | logD | = | 0.35 | ALA2209380 | ||||||
5. | ALA2203701 | [18F]-ST889 | Stability | = | 98 | % | ALA2209381 | % | Homo sapiens | |||
6. | ALA2203701 | [18F]-ST889 | Drug degradation | = | 3 | % | ALA2209382 | % | Homo sapiens | |||
7. | ALA2203701 | [18F]-ST889 | Stability | 0 | ALA2209383 | Stable | % | Homo sapiens | ||||
8. | ALA2203701 | [18F]-ST889 | Stability | 0 | ALA2209384 | Stable | % | Homo sapiens | ||||
9. | ALA2203701 | [18F]-ST889 | Stability | 0 | ALA2209791 | Stable | % | Rattus norvegicus | ||||
10. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211664 | Active | Rattus norvegicus | |||||
11. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211665 | Active | Rattus norvegicus | |||||
12. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211666 | Active | Rattus norvegicus | |||||
13. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211667 | Active | Rattus norvegicus | |||||
14. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211668 | Not Active | Rattus norvegicus | |||||
15. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211669 | Not Active | Rattus norvegicus | |||||
16. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211670 | Not Active | Rattus norvegicus | |||||
17. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211671 | Not Active | Rattus norvegicus | |||||
18. | ALA2203701 | [18F]-ST889 | Drug uptake | 0 | ALA2211672 | Not Active | Rattus norvegicus | |||||
19. | ALA2203701 | [18F]-ST889 | Ratio | = | 0.8 | ALA2211673 | ||||||
20. | ALA2203701 | [18F]-ST889 | Papp | = | 1.6 | 10'-7 cm/s | ALA2211674 | 10'-7 cm/s |