# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2204313 | D-Cl-amidine | Ratio | = | 13500 | /M/min | ALA2212942 | /M/min | Homo sapiens | |||
2. | ALA2204313 | D-Cl-amidine | Ratio | = | 270 | /M/min | ALA2212943 | /M/min | Homo sapiens | |||
3. | ALA2204313 | D-Cl-amidine | Ratio | = | 65 | /M/min | ALA2212941 | /M/min | Homo sapiens | |||
4. | ALA2204313 | D-Cl-amidine | Ratio | = | 1400 | /M/min | ALA2212939 | /M/min | Homo sapiens | |||
5. | ALA2204313 | D-Cl-amidine | Selectivity ratio | = | 50 | ALA2212940 | ||||||
6. | ALA2204313 | D-Cl-amidine | Selectivity ratio | = | 208 | ALA2212471 | ||||||
7. | ALA2204313 | D-Cl-amidine | Selectivity ratio | = | 10 | ALA2212470 | ||||||
8. | ALA2204313 | D-Cl-amidine | Activity | 0 | ALA2212465 | Non-toxic | Mus musculus | |||||
9. | ALA2204313 | D-Cl-amidine | MTD | > | 150 | mg kg-1 | ALA2212464 | mg kg-1 | Mus musculus | |||
10. | ALA2204313 | D-Cl-amidine | Activity | 0 | ALA2212463 | Active | Homo sapiens | |||||
11. | ALA2204313 | D-Cl-amidine | Activity | 0 | ALA2212462 | Active | Homo sapiens | |||||
12. | ALA2204313 | D-Cl-amidine | Activity | 0 | ALA2212460 | Not Active | Homo sapiens | |||||
13. | ALA2204313 | D-Cl-amidine | Activity | 0 | ALA2212458 | Dose-dependent effect | Homo sapiens | |||||
14. | ALA2204313 | D-Cl-amidine | t1/2 | = | 33 | min | ALA2212455 | hr | Mus musculus | |||
15. | ALA2204313 | D-Cl-amidine | Drug uptake | = | 21 | nM | ALA2212453 | nM | Mus musculus | |||
16. | ALA2204313 | D-Cl-amidine | Drug uptake | = | 10 | nM | ALA2212452 | nM | Mus musculus | |||
17. | ALA2204313 | D-Cl-amidine | Drug uptake | = | 10 | nM | ALA2212451 | nM | Mus musculus | |||
18. | ALA2204313 | D-Cl-amidine | INH | 0 | ALA2212450 | Active | % | Homo sapiens | ||||
19. | ALA2204313 | D-Cl-amidine | INH | 0 | ALA2212449 | Active | % | Homo sapiens |