# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2204360 | 5m, Lu AA21004 | CLH | = | 7.1 | L/hr/kg | ALA2215824 | mL.min-1.kg-1 | Rattus norvegicus | |||
2. | ALA2204360 | 5m, Lu AA21004 | F | = | 16 | % | ALA2215823 | % | Rattus norvegicus | |||
3. | ALA2204360 | 5m, Lu AA21004 | Ki | = | 23 | nM | ALA2215843 | 7.64 | nM | Homo sapiens | ||
4. | ALA2204360 | 5m, Lu AA21004 | Ki | = | 39 | nM | ALA2215842 | 7.41 | nM | Homo sapiens | ||
5. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 5.3 | nM | ALA2215841 | 8.28 | nM | Rattus norvegicus | ||
6. | ALA2204360 | 5m, Lu AA21004 | Ki | = | 3.7 | nM | ALA2215840 | 8.43 | nM | Homo sapiens | ||
7. | ALA2204360 | 5m, Lu AA21004 | Ki | = | 15 | nM | ALA2215839 | 7.82 | nM | Homo sapiens | ||
8. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 5.4 | nM | ALA2215838 | 8.27 | nM | Homo sapiens | ||
9. | ALA2204360 | 5m, Lu AA21004 | Activity | 0 | ALA2215368 | Not Active | Homo sapiens | |||||
10. | ALA2204360 | 5m, Lu AA21004 | Ki | = | 230 | nM | ALA2215366 | 6.64 | nM | Rattus norvegicus | ||
11. | ALA2204360 | 5m, Lu AA21004 | EC50 | = | 200 | nM | ALA2215367 | 6.70 | nM | Homo sapiens | ||
12. | ALA2204360 | 5m, Lu AA21004 | Efficacy | = | 96 | % | ALA2215365 | % | Homo sapiens | |||
13. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 890 | nM | ALA2215837 | 6.05 | nM | Rattus norvegicus | ||
14. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 140 | nM | ALA2215836 | 6.85 | nM | |||
15. | ALA2204360 | 5m, Lu AA21004 | Ratio IC50 | = | 170 | ALA2215847 | ||||||
16. | ALA2204360 | 5m, Lu AA21004 | Ratio IC50 | = | 26 | ALA2215835 | ||||||
17. | ALA2204360 | 5m, Lu AA21004 | CLH | = | 0.5 | L/min | ALA2215830 | L/min | Homo sapiens | |||
18. | ALA2204360 | 5m, Lu AA21004 | CLH | = | 55 | ml/min | ALA2215829 | ml/min | Rattus norvegicus | |||
19. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 40 | uM | ALA2215828 | 4.40 | nM | Homo sapiens | ||
20. | ALA2204360 | 5m, Lu AA21004 | IC50 | = | 39 | uM | ALA2215827 | 4.41 | nM | Homo sapiens |