| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2204933 | 6 | IC50 | = | 9.2 | nM | ALA2210526 | 8.04 | nM | Homo sapiens | ||
| 2. | ALA2204933 | 6 | IC50 | = | 58 | nM | ALA2210525 | 7.24 | nM | Homo sapiens | ||
| 3. | ALA2204933 | 6 | INH | = | 76 | % | ALA2208659 | % | Homo sapiens | |||
| 4. | ALA2204933 | 6 | IC50 | = | 8.1 | nM | ALA2210524 | 8.09 | nM | Mus musculus | ||
| 5. | ALA2204933 | 6 | IC50 | = | 29 | nM | ALA2210523 | 7.54 | nM | Mus musculus | ||
| 6. | ALA2204933 | 6 | Ki | = | 2206 | nM | ALA2210522 | 5.66 | nM | Homo sapiens | ||
| 7. | ALA2204933 | 6 | Activity | = | 87 | % | ALA2210521 | % | Mus musculus | |||
| 8. | ALA2204933 | 6 | Cp | = | 0.2 | uM | ALA2208661 | uM | Mus musculus | |||
| 9. | ALA2204933 | 6 | INH | = | 92 | % | ALA2208479 | % | Mus musculus | |||
| 10. | ALA2204933 | 6 | AUCt | = | 7.73 | uM.hr | ALA2210518 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 11. | ALA2204933 | 6 | t1/2 | = | 2.58 | hr | ALA2210517 | hr | Mus musculus | |||
| 12. | ALA2204933 | 6 | CL | = | 39.9 | ml/min.Kg | ALA2210516 | mL.min-1.kg-1 | Mus musculus | |||
| 13. | ALA2204933 | 6 | Vdss | = | 7.21 | L/Kg | ALA2210515 | L.kg-1 | Mus musculus | |||
| 14. | ALA2204933 | 6 | F | = | 76 | % | ALA2210514 | % | Mus musculus | |||
| 15. | ALA2204933 | 6 | AUCt | = | 4.36 | uM.hr | ALA2210513 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 16. | ALA2204933 | 6 | t1/2 | = | 8.14 | hr | ALA2210512 | hr | Rattus norvegicus | |||
| 17. | ALA2204933 | 6 | CL | = | 9.67 | ml/min.Kg | ALA2210511 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 18. | ALA2204933 | 6 | Vdss | = | 5.83 | L/Kg | ALA2210510 | L.kg-1 | Rattus norvegicus | |||
| 19. | ALA2204933 | 6 | F | = | 58 | % | ALA2210509 | % | Rattus norvegicus | |||
| 20. | ALA2204933 | 6 | AUCt | = | 27.6 | uM.hr | ALA2210519 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris |
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