# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2205766 | 14, CZC24758 | Activity | = | 30 | % | ALA2216354 | % | Mus musculus | |||
2. | ALA2205766 | 14, CZC24758 | CLH | = | 0.31 | ml/min/g | ALA2216331 | mL.min-1.g-1 | Rattus norvegicus | |||
3. | ALA2205766 | 14, CZC24758 | t1/2 | = | 1.2 | hr | ALA2216337 | hr | Rattus norvegicus | |||
4. | ALA2205766 | 14, CZC24758 | pIC50 | = | 1.3 | ALA2215895 | nM | Homo sapiens | ||||
5. | ALA2205766 | 14, CZC24758 | pIC50 | = | 1.3 | ALA2215896 | nM | Homo sapiens | ||||
6. | ALA2205766 | 14, CZC24758 | Vdss | = | 1.3 | L/Kg | ALA2216335 | L.kg-1 | Rattus norvegicus | |||
7. | ALA2205766 | 14, CZC24758 | CL | = | 1.6 | ml/min.kg | ALA2216342 | mL.min-1.kg-1 | Macaca fascicularis | |||
8. | ALA2205766 | 14, CZC24758 | pIC50 | = | 1.7 | ALA2215894 | nM | Homo sapiens | ||||
9. | ALA2205766 | 14, CZC24758 | Cmax | = | 2.5 | uM | ALA2216357 | nM | Mus musculus | |||
10. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.02 | ALA2211485 | 5.02 | nM | Homo sapiens | |||
11. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.03 | ALA2211976 | 5.03 | nM | Homo sapiens | |||
12. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.04 | ALA2211482 | 5.04 | nM | Homo sapiens | |||
13. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.23 | ALA2216361 | 5.23 | nM | Homo sapiens | |||
14. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.36 | ALA2211513 | 5.36 | nM | Homo sapiens | |||
15. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.61 | ALA2211980 | 5.61 | nM | Homo sapiens | |||
16. | ALA2205766 | 14, CZC24758 | Cmax | = | 5.9 | uM | ALA2216339 | nM | Rattus norvegicus | |||
17. | ALA2205766 | 14, CZC24758 | pIC50 | = | 5.97 | ALA2211988 | 5.97 | nM | Homo sapiens | |||
18. | ALA2205766 | 14, CZC24758 | t1/2 | = | 6.1 | hr | ALA2216343 | hr | Macaca fascicularis | |||
19. | ALA2205766 | 14, CZC24758 | pIC50 | = | 6.15 | ALA2211982 | 6.15 | nM | Homo sapiens | |||
20. | ALA2205766 | 14, CZC24758 | pIC50 | = | 6.3 | ALA2215897 | 6.30 | nM | Homo sapiens |