# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2207430 | 10f | beta t1/2 | = | 4.1 | hr | ALA2209555 | hr | Rattus norvegicus | |||
2. | ALA2207430 | 10f | CL | = | 4.8 | ml/min.kg | ALA2209542 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA2207430 | 10f | CLH | = | 122 | ml/min.kg | ALA2209548 | mL.min-1.kg-1 | Homo sapiens | |||
4. | ALA2207430 | 10f | Cmax | = | 621 | nM | ALA2209540 | nM | Rattus norvegicus | |||
5. | ALA2207430 | 10f | F | = | 1.6 | % | ALA2209538 | % | Rattus norvegicus | |||
6. | ALA2207430 | 10f | fCmax | = | 42 | nM | ALA2209539 | nM | Rattus norvegicus | |||
7. | ALA2207430 | 10f | Fu | = | 0.06 | ALA2209537 | Rattus norvegicus | |||||
8. | ALA2207430 | 10f | IC50 | > | 10000 | nM | ALA2209546 | nM | Homo sapiens | |||
9. | ALA2207430 | 10f | IC50 | = | 75 | nM | ALA2209550 | 7.12 | nM | Homo sapiens | ||
10. | ALA2207430 | 10f | IC50 | = | 283 | nM | ALA2209549 | 6.55 | nM | Mus musculus | ||
11. | ALA2207430 | 10f | INH | = | 4 | % | ALA2209547 | % | Homo sapiens | |||
12. | ALA2207430 | 10f | Vdss | = | 0.7 | L/Kg | ALA2209541 | L.kg-1 | Rattus norvegicus |