# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2207440 | 13j | beta t1/2 | = | 2 | hr | ALA2209555 | hr | Rattus norvegicus | |||
2. | ALA2207440 | 13j | CL | = | 2 | ml/min.kg | ALA2209542 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA2207440 | 13j | CLH | = | 55 | ml/min.kg | ALA2209548 | mL.min-1.kg-1 | Homo sapiens | |||
4. | ALA2207440 | 13j | Cmax | = | 61324 | nM | ALA2209540 | nM | Rattus norvegicus | |||
5. | ALA2207440 | 13j | F | = | 47 | % | ALA2209538 | % | Rattus norvegicus | |||
6. | ALA2207440 | 13j | fCmax | = | 184 | nM | ALA2209539 | nM | Rattus norvegicus | |||
7. | ALA2207440 | 13j | Fu | = | 0.003 | ALA2209537 | Rattus norvegicus | |||||
8. | ALA2207440 | 13j | IC50 | = | 6.4 | nM | ALA2209550 | 8.19 | nM | Homo sapiens | ||
9. | ALA2207440 | 13j | IC50 | = | 98 | nM | ALA2209549 | 7.01 | nM | Mus musculus | ||
10. | ALA2207440 | 13j | IC50 | = | 608 | nM | ALA2209546 | 6.22 | nM | Homo sapiens | ||
11. | ALA2207440 | 13j | INH | = | 31 | % | ALA2209547 | % | Homo sapiens | |||
12. | ALA2207440 | 13j | INH | 0 | ALA2209553 | Not Active | % | Homo sapiens | ||||
13. | ALA2207440 | 13j | INH | 0 | ALA2209554 | Not Active | % | Homo sapiens | ||||
14. | ALA2207440 | 13j | INH | 0 | ALA2209545 | Not Active | % | Homo sapiens | ||||
15. | ALA2207440 | 13j | INH | 0 | ALA2209544 | Not Active | % | Homo sapiens | ||||
16. | ALA2207440 | 13j | INH | 0 | ALA2209543 | Not Active | % | Homo sapiens | ||||
17. | ALA2207440 | 13j | logD | = | 5.2 | ALA2209551 | ||||||
18. | ALA2207440 | 13j | Vdss | = | 0.15 | L/Kg | ALA2209541 | L.kg-1 | Rattus norvegicus |