# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MK-591 sodium | 19 MK-591 | IC50 | = | 12 | nM | ALA1924647 | 7.92 | nM | Homo sapiens | ||
2. | MK-591 sodium | 19 MK-591 | IC50 | = | 66 | nM | ALA1924646 | 7.18 | nM | Homo sapiens | ||
3. | MK-591 sodium | 19 MK-591 | IC50 | = | 1 | nM | ALA1924645 | 9.00 | nM | Homo sapiens | ||
4. | MK-591 sodium | 19 MK-591 | IC50 | = | 1 | nM | ALA1924644 | 9.00 | nM | Homo sapiens | ||
5. | MK-591 sodium | 19 MK-591 | IC50 | = | 0.5 | nM | ALA1924524 | 9.30 | nM | Homo sapiens | ||
6. | MK-591 sodium | 19 MK-591 | IC50 | = | 80 | nM | ALA1924523 | 7.10 | nM | Homo sapiens | ||
7. | MK-591 sodium | 19 MK-591 | IC50 | = | 108 | nM | ALA1924522 | 6.97 | nM | Homo sapiens | ||
8. | MK-591 sodium | 19 MK-591 | IC50 | = | 536 | nM | ALA1924521 | 6.27 | nM | Homo sapiens | ||
9. | MK-591 sodium | 19 MK-591 | IC50 | = | 10 | nM | ALA1924520 | 8.00 | nM | Rattus norvegicus | ||
10. | MK-591 sodium | 19 MK-591 | IC50 | = | 117 | nM | ALA1924519 | 6.93 | nM | Rattus norvegicus | ||
11. | MK-591 sodium | 19 MK-591 | IC50 | = | 1.9 | nM | ALA1924518 | 8.72 | nM | Homo sapiens | ||
12. | MK-591 sodium | 19 MK-591 | ED50 | = | 1.6 | mg kg-1 | ALA779344 | mg.kg-1 | Rattus norvegicus | |||
13. | MK-591 sodium | 19 MK-591 | IC50 | = | 8 | nM | ALA696464 | 8.10 | nM | Homo sapiens | ||
14. | MK-591 sodium | 19 MK-591 | T1/2 | = | 6 | hr | ALA638978 | hr | ||||
15. | MK-591 sodium | 19 MK-591 | ED50 | = | 0.3 | mg kg-1 | ALA652029 | mg.kg-1 | ||||
16. | MK-591 sodium | 19 MK-591 | ED50 | = | 0.16 | mg kg-1 | ALA652030 | mg.kg-1 | ||||
17. | MK-591 sodium | 19 MK-591 | IC50 | = | 1.6 | nM | ALA784028 | 8.80 | nM | Rattus norvegicus | ||
18. | MK-591 sodium | 19 MK-591 | IC50 | = | 510 | nM | ALA701222 | 6.29 | nM | Homo sapiens | ||
19. | MK-591 sodium | 19 MK-591 | IC50 | = | 3 | nM | ALA767836 | 8.52 | nM | Homo sapiens | ||
20. | MK-591 sodium | 19 MK-591 | IC50 | = | 6 | nM | ALA769915 | 8.22 | nM | Rattus norvegicus |