| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2261361 | 8a | IC50 | = | 2.2 | nM | ALA3056377 | 8.66 | nM | Homo sapiens | ||
| 2. | ALA2261361 | 8a | Ki | = | 2.2 | nM | ALA3056377 | 8.66 | nM | Homo sapiens | ||
| 3. | ALA2261361 | 8a | IC50 | = | 683 | nM | ALA3056375 | 6.17 | nM | Homo sapiens | ||
| 4. | ALA2261361 | 8a | Ki | = | 1503 | nM | ALA3056375 | 5.82 | nM | Homo sapiens | ||
| 5. | ALA2261361 | 8a | CL | = | 1.7 | ml/min.kg | ALA3056376 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 6. | ALA2261361 | 8a | Vd | = | 0.16 | L/Kg | ALA3056367 | L.kg-1 | Rattus norvegicus | |||
| 7. | ALA2261361 | 8a | beta t1/2 | = | 1.1 | hr | ALA3056366 | hr | Rattus norvegicus | |||
| 8. | ALA2261361 | 8a | Drug metabolism | 0 | ALA3056364 | Active | Rattus norvegicus | |||||
| 9. | ALA2261361 | 8a | Drug metabolism | 0 | ALA3056365 | Active | Rattus norvegicus | |||||
| 10. | ALA2261361 | 8a | Cmax | = | 48 | ng/ml | ALA3057251 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 11. | ALA2261361 | 8a | Tmax | = | 0.25 | hr | ALA3056363 | hr | Rattus norvegicus | |||
| 12. | ALA2261361 | 8a | Cmax | = | 83 | ng/ml | ALA3057250 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 13. | ALA2261361 | 8a | Tmax | = | 4 | hr | ALA3057249 | hr | Rattus norvegicus | |||
| 14. | ALA2261361 | 8a | Drugabsorption | = | 36 | % | ALA3057248 | % | Rattus norvegicus | |||
| 15. | ALA2261361 | 8a | betat1/2(app) | = | 9 | hr | ALA3057247 | hr | Rattus norvegicus | |||
| 16. | ALA2261361 | 8a | t1/2 | > | 120 | min | ALA3057244 | hr | Rattus norvegicus | |||
| 17. | ALA2261361 | 8a | t1/2 | > | 120 | min | ALA3057245 | hr | Canis lupus familiaris | |||
| 18. | ALA2261361 | 8a | t1/2 | > | 120 | min | ALA3057246 | hr | Homo sapiens | |||
| 19. | ALA2261361 | 8a | Drug metabolism | 0 | ALA3057242 | Active | Homo sapiens | |||||
| 20. | ALA2261361 | 8a | Drug metabolism | 0 | ALA3057243 | Active | Rattus norvegicus |
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