Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2312645	11	IC50	=	0.52	uM	ALA2318063	6.28		nM	Homo sapiens
2.	ALA2312645	11	IC50	=	1.5	uM	ALA2318062	5.82		nM	Homo sapiens
3.	ALA2312645	11	IC50	=	8.8	uM	ALA2318061	5.06		nM
4.	ALA2312645	11	t1/2	=	34	min	ALA2318059			hr	Homo sapiens
5.	ALA2312645	11	t1/2	=	56	min	ALA2318060			hr	Rattus norvegicus
6.	ALA2312645	11	solubility	=	80	uM	ALA2317796			nM
7.	ALA2312645	11	permeability	=	1.2	ucm/s	ALA2317797			ucm/s
8.	ALA2312645	11	INH	=	27	%	ALA2318058			%	Homo sapiens
9.	ALA2312645	11	t1/2	=	3.5	hr	ALA2317795			hr	Rattus norvegicus
10.	ALA2312645	11	CL	=	73	ml/min.Kg	ALA2317793			mL.min-1.kg-1	Rattus norvegicus
11.	ALA2312645	11	Vdss	=	18	L/Kg	ALA2317794			L.kg-1	Rattus norvegicus
12.	ALA2312645	11	AUC	=	302	ng.hr/ml	ALA2317792			ng.hr.mL-1	Rattus norvegicus
13.	ALA2312645	11	Cmax	=	74	ng/ml	ALA2317791		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
14.	ALA2312645	11	F	=	41	%	ALA2317790			%	Rattus norvegicus
15.	ALA2312645	11	IC50	=	21.11	uM	ALA2317788	4.68		nM	Homo sapiens
16.	ALA2312645	11	IC50	=	30	uM	ALA2317787	4.52		nM	Homo sapiens
17.	ALA2312645	11	IC50	=	30	uM	ALA2317785	4.52		nM	Homo sapiens
18.	ALA2312645	11	IC50	=	30	uM	ALA2317786	4.52		nM	Homo sapiens
19.	ALA2312645	11	IC50		0		ALA2317784		Not Determined		Homo sapiens
20.	ALA2312645	11	IC50	=	30	uM	ALA2317783	4.52		nM	Homo sapiens