| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2312646 | 12 | IC50 | = | 0.27 | uM | ALA2318063 | 6.57 | nM | Homo sapiens | ||
| 2. | ALA2312646 | 12 | IC50 | = | 1.2 | uM | ALA2318062 | 5.92 | nM | Homo sapiens | ||
| 3. | ALA2312646 | 12 | IC50 | = | 7.2 | uM | ALA2318061 | 5.14 | nM | |||
| 4. | ALA2312646 | 12 | t1/2 | = | 14 | min | ALA2318059 | hr | Homo sapiens | |||
| 5. | ALA2312646 | 12 | t1/2 | = | 60 | min | ALA2318060 | hr | Rattus norvegicus | |||
| 6. | ALA2312646 | 12 | solubility | = | 7.8 | uM | ALA2317796 | nM | ||||
| 7. | ALA2312646 | 12 | permeability | = | 0.02 | ucm/s | ALA2317797 | ucm/s | ||||
| 8. | ALA2312646 | 12 | INH | = | 47 | % | ALA2318058 | % | Homo sapiens | |||
| 9. | ALA2312646 | 12 | t1/2 | = | 8 | hr | ALA2317795 | hr | Rattus norvegicus | |||
| 10. | ALA2312646 | 12 | CL | = | 40 | ml/min.Kg | ALA2317793 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 11. | ALA2312646 | 12 | Vdss | = | 25 | L/Kg | ALA2317794 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA2312646 | 12 | AUC | = | 680 | ng.hr/ml | ALA2317792 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA2312646 | 12 | Cmax | = | 35 | ng/ml | ALA2317791 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 14. | ALA2312646 | 12 | F | = | 32 | % | ALA2317790 | % | Rattus norvegicus | |||
| 15. | ALA2312646 | 12 | IC50 | = | 3.17 | uM | ALA2317788 | 5.50 | nM | Homo sapiens | ||
| 16. | ALA2312646 | 12 | IC50 | = | 18.58 | uM | ALA2317787 | 4.73 | nM | Homo sapiens | ||
| 17. | ALA2312646 | 12 | IC50 | = | 30 | uM | ALA2317785 | 4.52 | nM | Homo sapiens | ||
| 18. | ALA2312646 | 12 | IC50 | = | 25.67 | uM | ALA2317786 | 4.59 | nM | Homo sapiens | ||
| 19. | ALA2312646 | 12 | IC50 | 0 | ALA2317784 | Not Determined | Homo sapiens | |||||
| 20. | ALA2312646 | 12 | IC50 | = | 30 | uM | ALA2317783 | 4.52 | nM | Homo sapiens |
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