# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2312647 | 13 | IC50 | = | 0.19 | uM | ALA2318063 | 6.72 | nM | Homo sapiens | ||
2. | ALA2312647 | 13 | IC50 | > | 80 | uM | ALA2318062 | nM | Homo sapiens | |||
3. | ALA2312647 | 13 | IC50 | = | 8.5 | uM | ALA2318061 | 5.07 | nM | |||
4. | ALA2312647 | 13 | t1/2 | = | 38 | min | ALA2318059 | hr | Homo sapiens | |||
5. | ALA2312647 | 13 | t1/2 | = | 60 | min | ALA2318060 | hr | Rattus norvegicus | |||
6. | ALA2312647 | 13 | solubility | = | 200 | uM | ALA2317796 | nM | ||||
7. | ALA2312647 | 13 | permeability | < | 0.1 | ucm/s | ALA2317797 | ucm/s | ||||
8. | ALA2312647 | 13 | INH | > | 50 | % | ALA2318058 | % | Homo sapiens | |||
9. | ALA2312647 | 13 | t1/2 | = | 0.2 | hr | ALA2317795 | hr | Rattus norvegicus | |||
10. | ALA2312647 | 13 | CL | = | 40 | ml/min.Kg | ALA2317793 | mL.min-1.kg-1 | Rattus norvegicus | |||
11. | ALA2312647 | 13 | Vdss | = | 0.4 | L/Kg | ALA2317794 | L.kg-1 | Rattus norvegicus | |||
12. | ALA2312647 | 13 | AUC | = | 0 | ng.hr/ml | ALA2317792 | ng.hr.mL-1 | Rattus norvegicus | |||
13. | ALA2312647 | 13 | Cmax | = | 25 | ng/ml | ALA2317791 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
14. | ALA2312647 | 13 | F | = | 0 | % | ALA2317790 | % | Rattus norvegicus |