| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329601 | nM | ||||
| 2. | ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329600 | nM | Homo sapiens | |||
| 3. | ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329599 | nM | Homo sapiens | |||
| 4. | ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329598 | nM | Homo sapiens | |||
| 5. | ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329597 | nM | Homo sapiens | |||
| 6. | ALA2322207 | (3S,5R)-12 | IC50 | > | 30 | uM | ALA2329596 | nM | Homo sapiens | |||
| 7. | ALA2322207 | (3S,5R)-12 | IC50 | = | 0.003 | uM | ALA2327101 | 8.52 | nM | Homo sapiens | ||
| 8. | ALA2322207 | (3S,5R)-12 | IC50 | = | 0.004 | uM | ALA2327101 | 8.40 | nM | Homo sapiens | ||
| 9. | ALA2322207 | (3S,5R)-12 | IC50 | = | 0.025 | uM | ALA2327103 | 7.60 | nM | Homo sapiens | ||
| 10. | ALA2322207 | (3S,5R)-12 | t1/2 | = | 2.3 | hr | ALA2329593 | hr | Rattus norvegicus | |||
| 11. | ALA2322207 | (3S,5R)-12 | CL | = | 2.6 | L/hr/kg | ALA2329592 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA2322207 | (3S,5R)-12 | Time | = | 3.1 | hr | ALA2329587 | hr | Rattus norvegicus | |||
| 13. | ALA2322207 | (3S,5R)-12 | Vdss | = | 5.3 | L/Kg | ALA2329591 | L.kg-1 | Rattus norvegicus | |||
| 14. | ALA2322207 | (3S,5R)-12 | Time | = | 7.8 | hr | ALA2329586 | hr | Rattus norvegicus | |||
| 15. | ALA2322207 | (3S,5R)-12 | F | = | 18 | % | ALA2329594 | % | Rattus norvegicus | |||
| 16. | ALA2322207 | (3S,5R)-12 | Activity | = | 28 | mmHg | ALA2327104 | mmHg | Rattus norvegicus | |||
| 17. | ALA2322207 | (3S,5R)-12 | Activity | = | 58 | mmHg | ALA2329585 | mmHg | Rattus norvegicus | |||
| 18. | ALA2322207 | (3S,5R)-12 | Cmax | = | 222 | nM | ALA2329590 | nM | Rattus norvegicus | |||
| 19. | ALA2322207 | (3S,5R)-12 | AUC | = | 750 | nM.hr | ALA2329589 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 20. | ALA2322207 | (3S,5R)-12 | INH | 0 | ALA2329595 | tde | % | Homo sapiens |
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