| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 300 | nM | ALA2330921 | 6.52 | nM | Homo sapiens | ||
| 2. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 0.17 | uM | ALA2330927 | 6.77 | nM | Homo sapiens | ||
| 3. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330925 | nM | Homo sapiens | |||
| 4. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330924 | nM | Homo sapiens | |||
| 5. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330923 | nM | ||||
| 6. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330922 | nM | Homo sapiens | |||
| 7. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330920 | nM | Homo sapiens | |||
| 8. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | > | 30 | uM | ALA2330866 | nM | Homo sapiens | |||
| 9. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 1 | uM | ALA2330865 | 6.00 | nM | Homo sapiens | ||
| 10. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 1 | uM | ALA2330864 | 6.00 | nM | Homo sapiens | ||
| 11. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 1 | uM | ALA2330863 | 6.00 | nM | Homo sapiens | ||
| 12. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 14.5 | uM | ALA2330862 | 4.84 | nM | Homo sapiens | ||
| 13. | ALA2322611 | 12a, (3S,4S)-12a | F | = | 53 | % | ALA2330860 | % | Rattus norvegicus | |||
| 14. | ALA2322611 | 12a, (3S,4S)-12a | t1/2 | = | 2 | hr | ALA2330861 | hr | Rattus norvegicus | |||
| 15. | ALA2322611 | 12a, (3S,4S)-12a | Vdss | = | 2.8 | L/Kg | ALA2330859 | L.kg-1 | Rattus norvegicus | |||
| 16. | ALA2322611 | 12a, (3S,4S)-12a | Cmax | = | 1310 | nM | ALA2330858 | nM | Rattus norvegicus | |||
| 17. | ALA2322611 | 12a, (3S,4S)-12a | AUC | = | 4810 | nM.hr | ALA2330857 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 18. | ALA2322611 | 12a, (3S,4S)-12a | Activity | 0 | ALA2330856 | Dose-dependent effect | Rattus norvegicus | |||||
| 19. | ALA2322611 | 12a, (3S,4S)-12a | Activity | = | 15 | mmHg | ALA2330928 | mmHg | Rattus norvegicus | |||
| 20. | ALA2322611 | 12a, (3S,4S)-12a | Activity | = | 35 | mmHg | ALA2330855 | mmHg | Rattus norvegicus |
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