| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2324748 | SI-4, R175C1 | pKa | = | 7.4 | ALA4702838 | ||||||
| 2. | ALA2324748 | SI-4, R175C1 | Fu | = | 0.065 | % | ALA4702833 | |||||
| 3. | ALA2324748 | SI-4, R175C1 | CLH | = | 3.2 | ml/min.kg | ALA4702832 | mL.min-1.kg-1 | ||||
| 4. | ALA2324748 | SI-4, R175C1 | CLH | = | 271 | ml/min.kg | ALA4702830 | mL.min-1.kg-1 | ||||
| 5. | ALA2324748 | SI-4, R175C1 | Ratio | = | 0.64 | ALA4702829 | ||||||
| 6. | ALA2324748 | SI-4, R175C1 | Ratio | = | 0.82 | ALA4702827 | ||||||
| 7. | ALA2324748 | SI-4, R175C1 | Fu | = | 0.125 | % | ALA4702825 | |||||
| 8. | ALA2324748 | SI-4, R175C1 | logD | = | 1.1 | ALA4702823 | ||||||
| 9. | ALA2324748 | SI-4, R175C1 | Papp | = | 3.2 | 10^-6 cm/s | ALA4702822 | 10^-6 cm/s | ||||
| 10. | ALA2324748 | SI-4, R175C1 | pKa | = | 6.5 | ALA4702821 | ||||||
| 11. | ALA2324748 | SI-4, R175C1 | F | = | 52 | % | ALA4040175 | % | Homo sapiens | |||
| 12. | ALA2324748 | SI-4, R175C1 | Cmax | = | 0.67 | ng/ml | ALA4040174 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Homo sapiens | ||
| 13. | ALA2324748 | SI-4, R175C1 | t1/2 | = | 2.2 | hr | ALA4040173 | hr | Homo sapiens | |||
| 14. | ALA2324748 | SI-4, R175C1 | Vdss | = | 0.41 | L/Kg | ALA4040172 | L.kg-1 | Homo sapiens | |||
| 15. | ALA2324748 | SI-4, R175C1 | CL free | = | 55 | ml/min.kg | ALA4040171 | mL.min-1.kg-1 | Homo sapiens | |||
| 16. | ALA2324748 | SI-4, R175C1 | CL | = | 3.6 | ml/min.kg | ALA4040170 | mL.min-1.kg-1 | Homo sapiens | |||
| 17. | ALA2324748 | SI-4, R175C1 | FC | = | 1.83 | ALA4040169 | Homo sapiens | |||||
| 18. | ALA2324748 | SI-4, R175C1 | FC | = | 2.13 | ALA4040168 | Homo sapiens | |||||
| 19. | ALA2324748 | SI-4, R175C1 | FC | = | 2.05 | ALA4040167 | Homo sapiens | |||||
| 20. | ALA2324748 | SI-4, R175C1 | Tmax | = | 0.3 | hr | ALA4040162 | hr | Rattus norvegicus |
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