# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2331704 | 22 | IC50 | = | 5 | nM | ALA2344627 | 8.30 | nM | Homo sapiens | ||
2. | ALA2331704 | 22 | IC50 | = | 108 | nM | ALA2345044 | 6.97 | nM | Homo sapiens | ||
3. | ALA2331704 | 22 | INH | 0 | ALA3625365 | Active | % | Rattus norvegicus | ||||
4. | ALA2331704 | 22 | IC50 | = | 3 | nM | ALA3625364 | 8.52 | nM | |||
5. | ALA2331704 | 22 | IC50 | > | 50000 | nM | ALA3625353 | nM | Homo sapiens | |||
6. | ALA2331704 | 22 | IC50 | = | 11160 | nM | ALA3625352 | 4.95 | nM | Homo sapiens | ||
7. | ALA2331704 | 22 | IC50 | > | 10000 | nM | ALA3625351 | nM | Homo sapiens | |||
8. | ALA2331704 | 22 | t1/2 | = | 0.3 | hr | ALA3625350 | hr | Rattus norvegicus | |||
9. | ALA2331704 | 22 | CL | = | 177 | ml/min.kg | ALA3625349 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA2331704 | 22 | AUC/dose | = | 0.03 | uM.hr.Kg/mg | ALA3625348 | uM.hr.Kg/mg | Rattus norvegicus | |||
11. | ALA2331704 | 22 | F | = | 10 | % | ALA3625347 | % | Rattus norvegicus | |||
12. | ALA2331704 | 22 | CLH | = | 107 | ml/min.kg | ALA3625233 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA2331704 | 22 | IC50 | = | 219 | nM | ALA3624351 | 6.66 | nM | Homo sapiens | ||
14. | ALA2331704 | 22 | IC50 | = | 19 | nM | ALA3624350 | 7.72 | nM | Homo sapiens |