# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2332071 | 12k | IC50 | > | 20 | uM | ALA2341178 | nM | Homo sapiens | |||
2. | ALA2332071 | 12k | IC50 | > | 20 | uM | ALA2341177 | nM | Homo sapiens | |||
3. | ALA2332071 | 12k | INH | = | -37 | % | ALA2341175 | % | Homo sapiens | |||
4. | ALA2332071 | 12k | AUC | = | 0.6 | uM.hr | ALA2341164 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
5. | ALA2332071 | 12k | Cmax | = | 1.2 | uM | ALA2341163 | nM | Rattus norvegicus | |||
6. | ALA2332071 | 12k | t1/2 | = | 2.2 | hr | ALA2341165 | hr | Rattus norvegicus | |||
7. | ALA2332071 | 12k | t1/2 | = | 3 | min | ALA2341181 | hr | Homo sapiens | |||
8. | ALA2332071 | 12k | Vd | = | 3.5 | L/Kg | ALA2341166 | L.kg-1 | Rattus norvegicus | |||
9. | ALA2332071 | 12k | F | = | 4 | % | ALA2341162 | % | Rattus norvegicus | |||
10. | ALA2332071 | 12k | IC50 | = | 13 | nM | ALA2341182 | 7.89 | nM | Homo sapiens | ||
11. | ALA2332071 | 12k | INH | = | 51 | % | ALA2341172 | % | Homo sapiens | |||
12. | ALA2332071 | 12k | IC50 | = | 58 | nM | ALA2341176 | 7.24 | nM | Homo sapiens | ||
13. | ALA2332071 | 12k | CL | = | 63 | ml/min.kg | ALA2341167 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA2332071 | 12k | INH | = | 68 | % | ALA2341174 | % | Homo sapiens | |||
15. | ALA2332071 | 12k | INH | = | 82 | % | ALA2341173 | % | Homo sapiens | |||
16. | ALA2332071 | 12k | IC50 | = | 138 | nM | ALA2341183 | 6.86 | nM | |||
17. | ALA2332071 | 12k | IC50 | = | 3823 | nM | ALA2341180 | 5.42 | nM | |||
18. | ALA2332071 | 12k | IC50 | 0 | ALA2341179 | Not Determined | Homo sapiens | |||||
19. | ALA2332071 | 12k | solubility | 0 | ALA2341161 | soluble | ||||||
20. | ALA2332071 | 12k | pIC50 | = | 7.886 | ALA3404496 | 7.89 | nM | Homo sapiens |