# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | oxazine 89 | 89 | IC50 | = | 2820 | nM | ALA3888178 | 5.55 | 378154 | nM | Homo sapiens | |
2. | oxazine 89 | 89 | IC50 | = | 11.5 | nM | ALA3888178 | 7.94 | 378118 | nM | Homo sapiens | |
3. | oxazine 89 | 89 | IC50 | > | 400000 | nM | ALA3888177 | 377878 | nM | Homo sapiens | ||
4. | oxazine 89 | 89 | IC50 | = | 30.4 | nM | ALA3888176 | 7.52 | 377637 | nM | Homo sapiens | |
5. | oxazine 89 | 89 | INH | 0 | ALA5029782 | Active | % | |||||
6. | oxazine 89 | 89 | INH | 0 | ALA5029781 | Active | % | |||||
7. | oxazine 89 | 89 | Fu | = | 0.24 | ALA5029758 | ||||||
8. | oxazine 89 | 89 | IC50 | = | 0.012 | uM | ALA2353183 | 7.92 | nM | Homo sapiens | ||
9. | oxazine 89 | 89 | IC50 | = | 0.002 | uM | ALA2350618 | 8.70 | nM | Homo sapiens | ||
10. | oxazine 89 | 89 | Ratio IC50 | = | 6 | ALA2350617 | Homo sapiens | |||||
11. | oxazine 89 | 89 | Activity | = | 95 | % | ALA2350614 | % | Mus musculus | |||
12. | oxazine 89 | 89 | pKa | = | 7 | ALA2350611 | ||||||
13. | oxazine 89 | 89 | logD | = | 2.8 | ALA2350612 | ||||||
14. | oxazine 89 | 89 | logP | = | 2.9 | ALA2350610 | ||||||
15. | oxazine 89 | 89 | Ratio | = | 1.9 | ALA2350609 | Sus scrofa | |||||
16. | oxazine 89 | 89 | INH | = | 75 | % | ALA2350608 | % | Homo sapiens | |||
17. | oxazine 89 | 89 | Activity | = | 88 | % | ALA2350607 | % | Mus musculus | |||
18. | oxazine 89 | 89 | Activity | = | 78 | % | ALA2350606 | % | Mus musculus | |||
19. | oxazine 89 | 89 | Activity | 0 | ALA2350605 | Dose-dependent effect | Mus musculus | |||||
20. | oxazine 89 | 89 | BPR | = | 1 | ALA2350604 |