# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2347950 | 12 | Inhibition | = | 16.44 | % | ALA4296184 | Average; N=2 | % | Staphylococcus aureus | ||
2. | ALA2347950 | 12 | Inhibition | = | 6.38 | % | ALA4296188 | Average; N=2 | % | Acinetobacter baumannii | ||
3. | ALA2347950 | 12 | Inhibition | = | 11.76 | % | ALA4296187 | Average; N=2 | % | Pseudomonas aeruginosa | ||
4. | ALA2347950 | 12 | Inhibition | = | 18.42 | % | ALA4296186 | Average; N=2 | % | Klebsiella pneumoniae | ||
5. | ALA2347950 | 12 | Inhibition | = | 7.15 | % | ALA4296185 | Average; N=2 | % | Escherichia coli | ||
6. | ALA2347950 | 12 | Inhibition | = | -6.05 | % | ALA4296190 | Average; N=2 | % | Cryptococcus neoformans | ||
7. | ALA2347950 | 12 | Inhibition | = | 3.94 | % | ALA4296189 | Average; N=2 | % | Candida albicans | ||
8. | ALA2347950 | 12 | Inhibition | 30.2 | % | ALA4513102 | Not Active | % | Naegleria gruberi | |||
9. | ALA2347950 | 12 | MIC90 | = | 0.013 | uM | ALA4478346 | nM | ||||
10. | ALA2347950 | 12 | INH | 0 | ALA4036299 | Dose-dependent effect | % | |||||
11. | ALA2347950 | 12 | INH | 0 | ALA4036298 | Dose-dependent effect | % | |||||
12. | ALA2347950 | 12 | INH | 0 | ALA4036297 | Dose-dependent effect | % | |||||
13. | ALA2347950 | 12 | Selectivity Index | > | 764 | ALA4036296 | ||||||
14. | ALA2347950 | 12 | Selectivity Index | > | 236 | ALA4036295 | ||||||
15. | ALA2347950 | 12 | Selectivity Index | > | 3820 | ALA4036294 | ||||||
16. | ALA2347950 | 12 | Selectivity Index | > | 1910 | ALA4036293 | ||||||
17. | ALA2347950 | 12 | Selectivity Index | > | 1910 | ALA4036292 | ||||||
18. | ALA2347950 | 12 | TD50 | > | 14.9 | ug ml-1 | ALA4036291 | ug ml-1 | Homo sapiens | |||
19. | ALA2347950 | 12 | MBC90 | = | 0.015 | ug ml-1 | ALA4036290 | ug ml-1 | Mycobacteroides abscessus | |||
20. | ALA2347950 | 12 | MIC | > | 160 | ug ml-1 | ALA4036289 | ug.mL-1 | Staphylococcus aureus |