# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2348862 | 10b, CC214-2 | IC50 | > | 30000 | nM | ALA5216224 | nM | Homo sapiens | |||
2. | ALA2348862 | 10b, CC214-2 | IC50 | = | 315 | nM | ALA5216205 | 6.50 | nM | Homo sapiens | ||
3. | ALA2348862 | 10b, CC214-2 | IC50 | = | 386 | nM | ALA5216191 | 6.41 | nM | Homo sapiens | ||
4. | ALA2348862 | 10b, CC214-2 | IC50 | = | 106 | nM | ALA5216190 | 6.97 | nM | Homo sapiens | ||
5. | ALA2348862 | 10b, CC214-2 | IC50 | = | 0.106 | uM | ALA3587365 | 6.97 | nM | Homo sapiens | ||
6. | ALA2348862 | 10b, CC214-2 | IC50 | = | 0.39 | uM | ALA3587377 | 6.41 | nM | Homo sapiens | ||
7. | ALA2348862 | 10b, CC214-2 | INH | = | 85 | % | ALA3587381 | % | Mus musculus | |||
8. | ALA2348862 | 10b, CC214-2 | Ratio | = | 5.1 | ALA3587386 | Homo sapiens | |||||
9. | ALA2348862 | 10b, CC214-2 | INH | = | 71 | % | ALA3587390 | % | Mus musculus | |||
10. | ALA2348862 | 10b, CC214-2 | Ratio | = | 6.4 | ALA3587393 | Homo sapiens | |||||
11. | ALA2348862 | 10b, CC214-2 | IC50 | > | 30 | uM | ALA3587362 | nM | Homo sapiens | |||
12. | ALA2348862 | 10b, CC214-2 | INH | = | 88 | % | ALA3587378 | % | Mus musculus | |||
13. | ALA2348862 | 10b, CC214-2 | INH | = | 86 | % | ALA3587383 | % | Mus musculus | |||
14. | ALA2348862 | 10b, CC214-2 | Ratio | = | 5.2 | ALA3587387 | Homo sapiens | |||||
15. | ALA2348862 | 10b, CC214-2 | INH | = | 65 | % | ALA3587391 | % | Mus musculus | |||
16. | ALA2348862 | 10b, CC214-2 | Ratio | = | 9.3 | ALA3587461 | Homo sapiens | |||||
17. | ALA2348862 | 10b, CC214-2 | Stability | = | 100 | % | ALA3587366 | % | ||||
18. | ALA2348862 | 10b, CC214-2 | AUC | = | 28 | uM.hr | ALA3587375 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
19. | ALA2348862 | 10b, CC214-2 | CL | = | 8.1 | ml/min.kg | ALA3587371 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA2348862 | 10b, CC214-2 | TGI | 0 | ALA3587463 | Dose-dependent effect | Homo sapiens |