| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2348865 | 9a, CC214-1 | IC50 | = | 1380 | nM | ALA5216224 | 5.86 | nM | Homo sapiens | ||
| 2. | ALA2348865 | 9a, CC214-1 | IC50 | = | 18 | nM | ALA5216205 | 7.75 | nM | Homo sapiens | ||
| 3. | ALA2348865 | 9a, CC214-1 | IC50 | = | 40 | nM | ALA5216191 | 7.40 | nM | Homo sapiens | ||
| 4. | ALA2348865 | 9a, CC214-1 | IC50 | = | 2 | nM | ALA5216190 | 8.70 | nM | Homo sapiens | ||
| 5. | ALA2348865 | 9a, CC214-1 | INH | = | 60 | % | ALA4423149 | % | Homo sapiens | |||
| 6. | ALA2348865 | 9a, CC214-1 | INH | = | 60 | % | ALA4423148 | % | Homo sapiens | |||
| 7. | ALA2348865 | 9a, CC214-1 | INH | = | 60 | % | ALA4423147 | % | Homo sapiens | |||
| 8. | ALA2348865 | 9a, CC214-1 | Stability | = | 93 | % | ALA3587366 | % | ||||
| 9. | ALA2348865 | 9a, CC214-1 | F | = | 0.85 | % | ALA3587370 | % | Rattus norvegicus | |||
| 10. | ALA2348865 | 9a, CC214-1 | AUC | = | 0.11 | uM.hr | ALA3587369 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 11. | ALA2348865 | 9a, CC214-1 | Tmax | = | 1 | hr | ALA3587368 | hr | Rattus norvegicus | |||
| 12. | ALA2348865 | 9a, CC214-1 | Cmax | = | 0.024 | uM | ALA3587367 | nM | Rattus norvegicus | |||
| 13. | ALA2348865 | 9a, CC214-1 | CL | = | 32 | ml/min.kg | ALA3587371 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA2348865 | 9a, CC214-1 | IC50 | = | 0.002 | uM | ALA2352069 | 8.70 | nM | Homo sapiens | ||
| 15. | ALA2348865 | 9a, CC214-1 | IC50 | = | 1.38 | uM | ALA2352068 | 5.86 | nM | Homo sapiens | ||
| 16. | ALA2348865 | 9a, CC214-1 | IC50 | = | 0.04 | uM | ALA2352067 | 7.40 | nM | Homo sapiens | ||
| 17. | ALA2348865 | 9a, CC214-1 | IC50 | = | 0.018 | uM | ALA2352066 | 7.75 | nM | |||
| 18. | ALA2348865 | 9a, CC214-1 | IC50 | = | 0.224 | uM | ALA2352065 | 6.65 | nM | Homo sapiens | ||
| 19. | ALA2348865 | 9a, CC214-1 | Ratio IC50 | > | 65 | ALA2352064 | ||||||
| 20. | ALA2348865 | 9a, CC214-1 | F | = | 0.85 | % | ALA2352062 | % | Rattus norvegicus |
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