# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2349467 | (R)-34 | Fu | = | 0.1 | ALA2351998 | Rattus norvegicus | |||||
2. | ALA2349467 | (R)-34 | Fu | = | 0.12 | ALA2351996 | ||||||
3. | ALA2349467 | (R)-34 | Fu | = | 0.029 | ALA2351997 | Rattus norvegicus | |||||
4. | ALA2349467 | (R)-34 | Fu | = | 0.028 | ALA2351995 | ||||||
5. | ALA2349467 | (R)-34 | CLH | = | 20 | ml/min.kg | ALA2351994 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA2349467 | (R)-34 | CLH | = | 35 | ml/min.kg | ALA2351993 | mL.min-1.kg-1 | Cavia porcellus | |||
7. | ALA2349467 | (R)-34 | CLH | = | 15 | ml/min.kg | ALA2351992 | mL.min-1.kg-1 | ||||
8. | ALA2349467 | (R)-34 | CLH | = | 8.5 | ml/min.kg | ALA2351991 | mL.min-1.kg-1 | Homo sapiens | |||
9. | ALA2349467 | (R)-34 | Cp(f) | = | 33 | nM | ALA2351990 | nM | ||||
10. | ALA2349467 | (R)-34 | Cp(f) | = | 224 | nM | ALA2351989 | nM | ||||
11. | ALA2349467 | (R)-34 | Cp(f) | = | 1209 | nM | ALA2351988 | nM | ||||
12. | ALA2349467 | (R)-34 | Cp(f) | = | 2891 | nM | ALA2351987 | nM | ||||
13. | ALA2349467 | (R)-34 | Cp(f) | = | 4962 | nM | ALA2351986 | nM | ||||
14. | ALA2349467 | (R)-34 | Drug uptake(free) | = | 6.3 | nM | ALA2351712 | nM | ||||
15. | ALA2349467 | (R)-34 | Drug uptake(free) | = | 32 | nM | ALA2351711 | nM | ||||
16. | ALA2349467 | (R)-34 | Drug uptake(free) | = | 105 | nM | ALA2351710 | nM | ||||
17. | ALA2349467 | (R)-34 | Drug uptake(free) | = | 224 | nM | ALA2351709 | nM | ||||
18. | ALA2349467 | (R)-34 | Drug uptake(free) | = | 456 | nM | ALA2351708 | nM | ||||
19. | ALA2349467 | (R)-34 | K(p,uu,brain) | = | 0.19 | ALA2350223 | ||||||
20. | ALA2349467 | (R)-34 | K(p,uu,brain) | = | 0.14 | ALA2350222 |