| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2349468 | (R)-45 | Fu | 0 | ALA2351998 | Not Determined | Rattus norvegicus | |||||
| 2. | ALA2349468 | (R)-45 | Fu | = | 0.045 | ALA2351996 | ||||||
| 3. | ALA2349468 | (R)-45 | Fu | 0 | ALA2351997 | Not Determined | Rattus norvegicus | |||||
| 4. | ALA2349468 | (R)-45 | Fu | = | 0.006 | ALA2351995 | ||||||
| 5. | ALA2349468 | (R)-45 | CLH | = | 33 | ml/min.kg | ALA2351994 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 6. | ALA2349468 | (R)-45 | CLH | = | 35 | ml/min.kg | ALA2351993 | mL.min-1.kg-1 | Cavia porcellus | |||
| 7. | ALA2349468 | (R)-45 | CLH | = | 7.8 | ml/min.kg | ALA2351992 | mL.min-1.kg-1 | ||||
| 8. | ALA2349468 | (R)-45 | CLH | = | 3 | ml/min.kg | ALA2351991 | mL.min-1.kg-1 | Homo sapiens | |||
| 9. | ALA2349468 | (R)-45 | Cp(f) | = | 122 | nM | ALA2351985 | nM | ||||
| 10. | ALA2349468 | (R)-45 | Drug uptake | = | 195 | nM | ALA2350204 | nM | ||||
| 11. | ALA2349468 | (R)-45 | Activity | = | 29 | % | ALA2352848 | % | Cavia porcellus | |||
| 12. | ALA2349468 | (R)-45 | IC50 | = | 18 | nM | ALA2352293 | 7.75 | nM | Homo sapiens | ||
| 13. | ALA2349468 | (R)-45 | IC50 | = | 1259 | nM | ALA2352017 | 5.90 | nM | Homo sapiens | ||
| 14. | ALA2349468 | (R)-45 | Ratio IC50 | = | 69 | ALA2352016 | ||||||
| 15. | ALA2349468 | (R)-45 | EC50 | = | 8 | nM | ALA2352015 | 8.10 | nM | Homo sapiens | ||
| 16. | ALA2349468 | (R)-45 | Ratio | = | 26 | ALA2352014 | Sus scrofa | |||||
| 17. | ALA2349468 | (R)-45 | Papp | = | 17 | ucm/s | ALA2352013 | ucm/s | Sus scrofa | |||
| 18. | ALA2349468 | (R)-45 | CLH | = | 19 | ml/min.kg | ALA2352010 | mL.min-1.kg-1 | Mus musculus |
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