Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2349469	(R)-46	Fu	=	0.14		ALA2351998				Rattus norvegicus
2.	ALA2349469	(R)-46	Fu	=	0.12		ALA2351996
3.	ALA2349469	(R)-46	Fu		0		ALA2351997		Not Determined		Rattus norvegicus
4.	ALA2349469	(R)-46	Fu	=	0.018		ALA2351995
5.	ALA2349469	(R)-46	CLH	=	60	ml/min.kg	ALA2351994			mL.min-1.kg-1	Rattus norvegicus
6.	ALA2349469	(R)-46	CLH	=	26	ml/min.kg	ALA2351993			mL.min-1.kg-1	Cavia porcellus
7.	ALA2349469	(R)-46	CLH	=	12	ml/min.kg	ALA2351992			mL.min-1.kg-1
8.	ALA2349469	(R)-46	CLH	=	3	ml/min.kg	ALA2351991			mL.min-1.kg-1	Homo sapiens
9.	ALA2349469	(R)-46	Cp(f)	=	304	nM	ALA2351984			nM
10.	ALA2349469	(R)-46	Cp(f)	=	562	nM	ALA2351983			nM
11.	ALA2349469	(R)-46	Drug uptake(free)	=	11	nM	ALA2351707			nM
12.	ALA2349469	(R)-46	K(p,uu,brain)	=	0.037		ALA2350218
13.	ALA2349469	(R)-46	Drug uptake	=	20	nM	ALA2350203			nM
14.	ALA2349469	(R)-46	Drug uptake	=	247	nM	ALA2350201			nM
15.	ALA2349469	(R)-46	Ratio	=	1.2		ALA2349934
16.	ALA2349469	(R)-46	Activity		0		ALA2352847		Not Active		Cavia porcellus
17.	ALA2349469	(R)-46	Activity	=	50	%	ALA2352846			%	Cavia porcellus
18.	ALA2349469	(R)-46	IC50	=	30	nM	ALA2352293	7.52		nM	Homo sapiens
19.	ALA2349469	(R)-46	IC50	=	990	nM	ALA2352017	6.00		nM	Homo sapiens
20.	ALA2349469	(R)-46	Ratio IC50	=	47		ALA2352016