| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2376303 | (S)-10 | pIC50 | = | 8.2 | ALA2378971 | 8.20 | nM | Homo sapiens | |||
| 2. | ALA2376303 | (S)-10 | pIC50 | = | 7.3 | ALA2378967 | 7.30 | nM | Homo sapiens | |||
| 3. | ALA2376303 | (S)-10 | pKa | = | 7.3 | ALA2378965 | ||||||
| 4. | ALA2376303 | (S)-10 | CLH | < | 5 | microL/min/mg | ALA2378966 | mL.min-1.g-1 | Homo sapiens | |||
| 5. | ALA2376303 | (S)-10 | Papp | = | 3.3 | ucm/s | ALA2378964 | ucm/s | Homo sapiens | |||
| 6. | ALA2376303 | (S)-10 | Ratio | = | 0.3 | ALA2378962 | Homo sapiens | |||||
| 7. | ALA2376303 | (S)-10 | INH | 0 | ALA2378961 | Not Active | % | |||||
| 8. | ALA2376303 | (S)-10 | INH | 0 | ALA2378960 | Not Active | % | |||||
| 9. | ALA2376303 | (S)-10 | Drug metabolism | = | 80 | % | ALA2378959 | % | Homo sapiens | |||
| 10. | ALA2376303 | (S)-10 | pIC50 | < | 5 | ALA2378958 | nM | Homo sapiens | ||||
| 11. | ALA2376303 | (S)-10 | pIC50 | < | 5 | ALA2378957 | nM | Homo sapiens | ||||
| 12. | ALA2376303 | (S)-10 | pIC50 | < | 4 | ALA2378918 | nM | Homo sapiens | ||||
| 13. | ALA2376303 | (S)-10 | pIC50 | < | 4 | ALA2378804 | nM | Homo sapiens | ||||
| 14. | ALA2376303 | (S)-10 | pIC50 | = | 7.9 | ALA2378803 | 7.90 | nM | Homo sapiens | |||
| 15. | ALA2376303 | (S)-10 | pIC50 | = | 7.1 | ALA2378802 | 7.10 | nM | Mus musculus | |||
| 16. | ALA2376303 | (S)-10 | Tmax | = | 30 | min | ALA2378801 | hr | Mus musculus | |||
| 17. | ALA2376303 | (S)-10 | INH | = | 68 | % | ALA2378800 | % | Mus musculus | |||
| 18. | ALA2376303 | (S)-10 | INH | = | 116 | % | ALA2378799 | % | Mus musculus | |||
| 19. | ALA2376303 | (S)-10 | pIC50 | = | 8.3 | ALA2378969 | 8.30 | nM | Mus musculus | |||
| 20. | ALA2376303 | (S)-10 | IC50 | = | 6.3 | nM | ALA4371681 | 8.20 | nM | Homo sapiens |
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