Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2380586	32a	IC50	=	10.4	nM	ALA2383388	7.98		nM	Homo sapiens
2.	ALA2380586	32a	IC50	=	37	nM	ALA2383387	7.43		nM	Homo sapiens
3.	ALA2380586	32a	Ratio IC50	=	3.6		ALA2383386
4.	ALA2380586	32a	IC50	=	20.5	nM	ALA2383385	7.69		nM	Homo sapiens
5.	ALA2380586	32a	IC50	=	152	nM	ALA2383384	6.82		nM	Homo sapiens
6.	ALA2380586	32a	log K	=	0.92		ALA2383383
7.	ALA2380586	32a	Papp	=	2.69	ucm/s	ALA2383382			ucm/s	Canis lupus familiaris
8.	ALA2380586	32a	INH	>	50	%	ALA2383380			%	Homo sapiens
9.	ALA2380586	32a	INH	>	50	%	ALA2383379			%	Homo sapiens
10.	ALA2380586	32a	INH	>	50	%	ALA2383378			%	Homo sapiens
11.	ALA2380586	32a	INH	>	50	%	ALA2383377			%	Homo sapiens
12.	ALA2380586	32a	INH	>	50	%	ALA2383376			%	Homo sapiens
13.	ALA2380586	32a	INH	>	50	%	ALA2383375			%	Homo sapiens
14.	ALA2380586	32a	IC50	>	5	uM	ALA2383371			nM	Homo sapiens
15.	ALA2380586	32a	Stability	=	69	%	ALA2383365			%	Rattus norvegicus
16.	ALA2380586	32a	CL	=	33	ml/min.kg	ALA2383364			mL.min-1.kg-1	Rattus norvegicus
17.	ALA2380586	32a	Vdss	=	2.8	L/Kg	ALA2383363			L.kg-1	Rattus norvegicus
18.	ALA2380586	32a	AUC	=	11.5	ng.hr/ml	ALA2383362			ng.hr.mL-1	Rattus norvegicus
19.	ALA2380586	32a	Cmax	=	1.4	ng/ml	ALA2383361		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
20.	ALA2380586	32a	F	=	2.3	%	ALA2383360			%	Rattus norvegicus