# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2380587 | 32b | IC50 | = | 12 | nM | ALA2383388 | 7.92 | nM | Homo sapiens | ||
2. | ALA2380587 | 32b | IC50 | = | 12.1 | nM | ALA2383387 | 7.92 | nM | Homo sapiens | ||
3. | ALA2380587 | 32b | Ratio IC50 | = | 1 | ALA2383386 | ||||||
4. | ALA2380587 | 32b | IC50 | = | 30.4 | nM | ALA2383385 | 7.52 | nM | Homo sapiens | ||
5. | ALA2380587 | 32b | IC50 | = | 283 | nM | ALA2383384 | 6.55 | nM | Homo sapiens | ||
6. | ALA2380587 | 32b | log K | = | 0.94 | ALA2383383 | ||||||
7. | ALA2380587 | 32b | Papp | = | 20.5 | ucm/s | ALA2383382 | ucm/s | Canis lupus familiaris | |||
8. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383380 | % | Homo sapiens | |||
9. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383379 | % | Homo sapiens | |||
10. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383378 | % | Homo sapiens | |||
11. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383374 | % | Homo sapiens | |||
12. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383373 | % | Homo sapiens | |||
13. | ALA2380587 | 32b | INH | > | 50 | % | ALA2383372 | % | Homo sapiens | |||
14. | ALA2380587 | 32b | IC50 | > | 5 | uM | ALA2383371 | nM | Homo sapiens | |||
15. | ALA2380587 | 32b | Stability | = | 64 | % | ALA2383365 | % | Rattus norvegicus | |||
16. | ALA2380587 | 32b | CL | = | 19 | ml/min.kg | ALA2383364 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA2380587 | 32b | Vdss | = | 1 | L/Kg | ALA2383363 | L.kg-1 | Rattus norvegicus | |||
18. | ALA2380587 | 32b | AUC | = | 149 | ng.hr/ml | ALA2383362 | ng.hr.mL-1 | Rattus norvegicus | |||
19. | ALA2380587 | 32b | Cmax | = | 18 | ng/ml | ALA2383361 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
20. | ALA2380587 | 32b | F | = | 17 | % | ALA2383360 | % | Rattus norvegicus |