| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2381946 | 40 | IC50 | = | 0.001 | uM | ALA2384487 | 9.00 | nM | Homo sapiens | ||
| 2. | ALA2381946 | 40 | IC50 | > | 85 | uM | ALA2384485 | nM | Homo sapiens | |||
| 3. | ALA2381946 | 40 | EC50 | = | 0.061 | uM | ALA2384483 | 7.21 | nM | Homo sapiens | ||
| 4. | ALA2381946 | 40 | IC50 | = | 0.15 | uM | ALA2384482 | 6.82 | nM | Homo sapiens | ||
| 5. | ALA2381946 | 40 | CLH | < | 14 | microL/min/mg | ALA2384481 | mL.min-1.g-1 | Homo sapiens | |||
| 6. | ALA2381946 | 40 | CLH | = | 45 | microL/min/mg | ALA2384480 | mL.min-1.g-1 | Rattus norvegicus | |||
| 7. | ALA2381946 | 40 | solubility | = | 13 | ug ml-1 | ALA2384346 | ug.mL-1 | ||||
| 8. | ALA2381946 | 40 | solubility | = | 12 | ug ml-1 | ALA2384345 | ug.mL-1 | ||||
| 9. | ALA2381946 | 40 | PPB | = | 94.9 | % | ALA2384341 | % | Mus musculus | |||
| 10. | ALA2381946 | 40 | EC50 | = | 0.061 | uM | ALA2384334 | 7.21 | nM | Homo sapiens | ||
| 11. | ALA2381946 | 40 | IC50 | = | 5.4 | uM | ALA2384333 | 5.27 | nM | Homo sapiens | ||
| 12. | ALA2381946 | 40 | Activity | = | 74 | % | ALA2384332 | % | Rattus norvegicus | |||
| 13. | ALA2381946 | 40 | Ratio | = | 23 | ALA2384331 | ||||||
| 14. | ALA2381946 | 40 | Drug uptake | = | 2.2 | uM | ALA2384328 | uM | Mus musculus | |||
| 15. | ALA2381946 | 40 | Drug uptake | = | 0.1 | uM | ALA2384329 | uM | Mus musculus | |||
| 16. | ALA2381946 | 40 | Ratio EC50 | = | 40 | ALA2384327 | ||||||
| 17. | ALA2381946 | 40 | solubility | = | 24 | ug ml-1 | ALA2384347 | ug.mL-1 | ||||
| 18. | ALA2381946 | 40 | IC50 | > | 170 | uM | ALA2384484 | nM | Homo sapiens | |||
| 19. | ALA2381946 | 40 | AUCt | = | 101 | uM.hr | ALA2384339 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 20. | ALA2381946 | 40 | Cmax | = | 27.4 | uM | ALA2384340 | nM | Mus musculus |
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