| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2381959 | 21 | IC50 | = | 0.018 | uM | ALA2384487 | 7.75 | nM | Homo sapiens | ||
| 2. | ALA2381959 | 21 | EC50 | = | 1.01 | uM | ALA2384483 | 6.00 | nM | Homo sapiens | ||
| 3. | ALA2381959 | 21 | IC50 | = | 0.189 | uM | ALA2384482 | 6.72 | nM | Homo sapiens | ||
| 4. | ALA2381959 | 21 | CLH | = | 55 | microL/min/mg | ALA2384481 | mL.min-1.g-1 | Homo sapiens | |||
| 5. | ALA2381959 | 21 | CLH | = | 61 | microL/min/mg | ALA2384480 | mL.min-1.g-1 | Rattus norvegicus | |||
| 6. | ALA2381959 | 21 | t1/2 | = | 238 | min | ALA2384349 | hr | Mus musculus | |||
| 7. | ALA2381959 | 21 | solubility | = | 171 | ug ml-1 | ALA2384346 | ug.mL-1 | ||||
| 8. | ALA2381959 | 21 | solubility | = | 9 | ug ml-1 | ALA2384347 | ug.mL-1 | ||||
| 9. | ALA2381959 | 21 | solubility | = | 1 | ug ml-1 | ALA2384345 | ug.mL-1 | ||||
| 10. | ALA2381959 | 21 | Papp | = | 17.1 | ucm/s | ALA2384344 | ucm/s | Sus scrofa | |||
| 11. | ALA2381959 | 21 | Ratio | = | 1 | ALA2384343 | Sus scrofa | |||||
| 12. | ALA2381959 | 21 | AUCt | = | 0.17 | uM.hr | ALA2384339 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 13. | ALA2381959 | 21 | Cmax | = | 0.37 | uM | ALA2384340 | nM | Mus musculus | |||
| 14. | ALA2381959 | 21 | CL | = | 1.3 | L/hr/kg | ALA2384336 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 15. | ALA2381959 | 21 | PPB | 0 | ALA2384342 | Not Determined | % | Rattus norvegicus | ||||
| 16. | ALA2381959 | 21 | PPB | 0 | ALA2384341 | Not Determined | % | Mus musculus | ||||
| 17. | ALA2381959 | 21 | IC50 | = | 11 | nM | ALA3888462 | 7.96 | 403257 | nM | Homo sapiens | |
| 18. | ALA2381959 | 21 | IC50 | = | 18.3 | nM | ALA3888461 | 7.74 | 403076 | nM | Homo sapiens |
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