| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2382212 | 8g | IC50 | > | 40 | uM | ALA2383147 | nM | Leishmania donovani | |||
| 2. | ALA2382212 | 8g | IC50 | = | 4.39 | uM | ALA2384797 | 5.36 | nM | Leishmania donovani | ||
| 3. | ALA2382212 | 8g | CC50 | > | 400 | uM | ALA2384796 | nM | ||||
| 4. | ALA2382212 | 8g | CC50 | > | 400 | uM | ALA2384795 | nM | Chlorocebus sabaeus | |||
| 5. | ALA2382212 | 8g | Ratio CC50/IC50 | > | 91.11 | ALA2384794 | ||||||
| 6. | ALA2382212 | 8g | logP | = | 7.19 | ALA2384791 | ||||||
| 7. | ALA2382212 | 8g | FC | > | 8 | ALA2384792 | ||||||
| 8. | ALA2382212 | 8g | FC | = | 11 | ALA2384790 | ||||||
| 9. | ALA2382212 | 8g | FC | = | 5 | ALA2384789 | ||||||
| 10. | ALA2382212 | 8g | FC | > | 3 | ALA2384788 | ||||||
| 11. | ALA2382212 | 8g | Activity | = | 22.58 | uM | ALA2384787 | uM | ||||
| 12. | ALA2382212 | 8g | INH | = | 80.93 | % | ALA2384786 | % | Leishmania donovani | |||
| 13. | ALA2382212 | 8g | KSV | = | 6 | 10'4L/mol | ALA2384783 | 10'4L/mol | Bos taurus | |||
| 14. | ALA2382212 | 8g | Cmax | = | 63276.38 | ng/ml | ALA2384779 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 15. | ALA2382212 | 8g | Tmax | = | 0.08 | hr | ALA2384778 | hr | Rattus norvegicus | |||
| 16. | ALA2382212 | 8g | AUCt | = | 716 | ng.hr/ml | ALA2384776 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA2382212 | 8g | AUCt | = | 24341 | ng.hr/ml | ALA2384774 | ng.hr.mL-1 | Rattus norvegicus | |||
| 18. | ALA2382212 | 8g | beta t1/2 | = | 12.79 | hr | ALA2384651 | hr | Rattus norvegicus | |||
| 19. | ALA2382212 | 8g | MRT | = | 8.44 | hr | ALA2384650 | hr | Rattus norvegicus | |||
| 20. | ALA2382212 | 8g | MRT | = | 5.88 | hr | ALA2384649 | hr | Rattus norvegicus |
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