Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2385460	26, AM-5262	Activity		0		ALA5240318		Active		Homo sapiens
2.	ALA2385460	26, AM-5262	Efficacy	=	-25	%	ALA5240316			%	Homo sapiens
3.	ALA2385460	26, AM-5262	Efficacy	=	-25	%	ALA5240315			%	Homo sapiens
4.	ALA2385460	26, AM-5262	EC50	=	1.3	nM	ALA5240307	8.89		nM	Homo sapiens
5.	ALA2385460	26, AM-5262	EC50	=	0.081	uM	ALA2388543	7.09		nM	Homo sapiens
6.	ALA2385460	26, AM-5262	Emax	=	101	%	ALA2388542			%	Homo sapiens
7.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388541			%	Homo sapiens
8.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388540			%	Homo sapiens
9.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388539			%	Homo sapiens
10.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388538			%	Homo sapiens
11.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388537			%	Homo sapiens
12.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388536			%	Homo sapiens
13.	ALA2385460	26, AM-5262	INH	<	70	%	ALA2388535			%	Rattus norvegicus
14.	ALA2385460	26, AM-5262	F	=	28	%	ALA2388528			%	Rattus norvegicus
15.	ALA2385460	26, AM-5262	F	=	69	%	ALA2388527			%	Macaca fascicularis
16.	ALA2385460	26, AM-5262	Activity	=	48	%	ALA2389865			%	Mus musculus
17.	ALA2385460	26, AM-5262	t1/2	=	4.2	hr	ALA2388530			hr	Rattus norvegicus
18.	ALA2385460	26, AM-5262	t1/2	=	2.2	hr	ALA2388529			hr	Macaca fascicularis
19.	ALA2385460	26, AM-5262	CL	=	0.25	L/hr/kg	ALA2388534			mL.min-1.kg-1	Rattus norvegicus
20.	ALA2385460	26, AM-5262	CL	=	0.84	L/hr/kg	ALA2388533			mL.min-1.kg-1	Macaca fascicularis