# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2385464 | 30 | EC50 | = | 0.105 | uM | ALA2388543 | 6.98 | nM | Homo sapiens | ||
2. | ALA2385464 | 30 | Emax | = | 90 | % | ALA2388542 | % | Homo sapiens | |||
3. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388541 | % | Homo sapiens | |||
4. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388540 | % | Homo sapiens | |||
5. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388539 | % | Homo sapiens | |||
6. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388538 | % | Homo sapiens | |||
7. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388537 | % | Homo sapiens | |||
8. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388536 | % | Homo sapiens | |||
9. | ALA2385464 | 30 | INH | < | 70 | % | ALA2388535 | % | Rattus norvegicus | |||
10. | ALA2385464 | 30 | F | = | 61 | % | ALA2388528 | % | Rattus norvegicus | |||
11. | ALA2385464 | 30 | F | = | 44 | % | ALA2388527 | % | Macaca fascicularis | |||
12. | ALA2385464 | 30 | t1/2 | = | 4.1 | hr | ALA2388530 | hr | Rattus norvegicus | |||
13. | ALA2385464 | 30 | t1/2 | = | 3.7 | hr | ALA2388529 | hr | Macaca fascicularis | |||
14. | ALA2385464 | 30 | CL | = | 0.17 | L/hr/kg | ALA2388534 | mL.min-1.kg-1 | Rattus norvegicus | |||
15. | ALA2385464 | 30 | CL | = | 0.11 | L/hr/kg | ALA2388533 | mL.min-1.kg-1 | Macaca fascicularis | |||
16. | ALA2385464 | 30 | Vdss | = | 0.8 | L/Kg | ALA2388532 | L.kg-1 | Rattus norvegicus | |||
17. | ALA2385464 | 30 | Vdss | = | 0.4 | L/Kg | ALA2388531 | L.kg-1 | Macaca fascicularis |