| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2386849 | 2 | Activity | 0 | ALA4039314 | Not Active | Rattus norvegicus | |||||
| 2. | ALA2386849 | 2 | Ratio IC50 | > | 400 | ALA4039256 | ||||||
| 3. | ALA2386849 | 2 | IC50 | = | 1.38 | uM | ALA4039255 | 5.86 | nM | Homo sapiens | ||
| 4. | ALA2386849 | 2 | IC50 | = | 1.54 | uM | ALA4039254 | 5.81 | nM | Homo sapiens | ||
| 5. | ALA2386849 | 2 | INH | = | 86 | % | ALA4039253 | % | Homo sapiens | |||
| 6. | ALA2386849 | 2 | Activity | 0 | ALA4039251 | Not Active | Rattus norvegicus | |||||
| 7. | ALA2386849 | 2 | Activity | 0 | ALA4039250 | Not Active | Rattus norvegicus | |||||
| 8. | ALA2386849 | 2 | Activity | 0 | ALA4039249 | Not Active | Rattus norvegicus | |||||
| 9. | ALA2386849 | 2 | Activity | 0 | ALA4039248 | Not Active | Rattus norvegicus | |||||
| 10. | ALA2386849 | 2 | Activity | 0 | ALA4039247 | Not Active | Rattus norvegicus | |||||
| 11. | ALA2386849 | 2 | Activity | 0 | ALA4039246 | Not Active | Rattus norvegicus | |||||
| 12. | ALA2386849 | 2 | F | = | 35 | % | ALA4039245 | % | Macaca fascicularis | |||
| 13. | ALA2386849 | 2 | AUC | = | 6.43 | uM.hr | ALA4039244 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Macaca fascicularis | ||
| 14. | ALA2386849 | 2 | Cmax | = | 1.36 | uM | ALA4039243 | nM | Macaca fascicularis | |||
| 15. | ALA2386849 | 2 | Tmax | = | 120 | min | ALA4039242 | hr | Macaca fascicularis | |||
| 16. | ALA2386849 | 2 | Vdss | = | 4 | L/Kg | ALA4039241 | L.kg-1 | Macaca fascicularis | |||
| 17. | ALA2386849 | 2 | CL | = | 13.3 | ml/min.kg | ALA4039240 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 18. | ALA2386849 | 2 | MRT | = | 303 | min | ALA4039239 | hr | Macaca fascicularis | |||
| 19. | ALA2386849 | 2 | beta t1/2 | = | 563 | min | ALA4039238 | hr | Macaca fascicularis | |||
| 20. | ALA2386849 | 2 | F | = | 71 | % | ALA4039237 | % | Rattus norvegicus |
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