# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2387078 | 18e | Ki | = | 1.5 | nM | ALA2389082 | 8.82 | nM | Homo sapiens | ||
2. | ALA2387078 | 18e | Ki | = | 890 | nM | ALA2389081 | 6.05 | nM | Homo sapiens | ||
3. | ALA2387078 | 18e | IC50 | = | 1.4 | nM | ALA2389080 | 8.85 | nM | Homo sapiens | ||
4. | ALA2387078 | 18e | Emax | = | 100 | % | ALA2389078 | % | Homo sapiens | |||
5. | ALA2387078 | 18e | Ratio Ki | = | 593 | ALA2389076 | ||||||
6. | ALA2387078 | 18e | Vdss | = | 2.29 | L/Kg | ALA2389074 | L.kg-1 | Mus musculus | |||
7. | ALA2387078 | 18e | CL | = | 96 | ml/min.kg | ALA2389073 | mL.min-1.kg-1 | Mus musculus | |||
8. | ALA2387078 | 18e | t1/2 | = | 0.28 | hr | ALA2389071 | hr | Mus musculus | |||
9. | ALA2387078 | 18e | AUC | = | 390 | ng.hr/ml | ALA2389069 | ng.hr.mL-1 | Mus musculus | |||
10. | ALA2387078 | 18e | Cmax | = | 168 | ng/ml | ALA2389068 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
11. | ALA2387078 | 18e | F | = | 25 | % | ALA2388850 | % | Mus musculus | |||
12. | ALA2387078 | 18e | INH | = | 81 | % | ALA2389067 | % | Mus musculus | |||
13. | ALA2387078 | 18e | Activity | 0 | ALA2388849 | Non-toxic | Mus musculus | |||||
14. | ALA2387078 | 18e | Activity | 0 | ALA2388690 | Active | Mus musculus |