# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2387269 | 48, P218 | IC50 | < | 1 | uM | ALA2433135 | nM | Plasmodium yoelii | |||
2. | ALA2387269 | 48, P218 | INH | 0 | ALA2433134 | Not Determined | % | Plasmodium falciparum | ||||
3. | ALA2387269 | 48, P218 | INH | 0 | ALA2433133 | Not Determined | % | Plasmodium berghei | ||||
4. | ALA2387269 | 48, P218 | IC50 | = | 4.6 | nM | ALA2390431 | 8.34 | nM | Plasmodium falciparum | ||
5. | ALA2387269 | 48, P218 | IC50 | = | 56 | nM | ALA2390430 | 7.25 | nM | Plasmodium falciparum | ||
6. | ALA2387269 | 48, P218 | ED50 | = | 0.3 | mg/kg/day | ALA2390429 | mg/kg/day | Plasmodium falciparum | |||
7. | ALA2387269 | 48, P218 | F | = | 46 | % | ALA2390428 | % | Rattus norvegicus | |||
8. | ALA2387269 | 48, P218 | t1/2 | = | 7.3 | hr | ALA2390427 | hr | Rattus norvegicus | |||
9. | ALA2387269 | 48, P218 | IC50 | = | 4.6 | nM | ALA4181677 | 8.34 | nM | Plasmodium falciparum K1 |