| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2387397 | 45 | Activity | = | 1.3 | % | ALA2388095 | % | Rattus norvegicus | |||
| 2. | ALA2387397 | 45 | FC | = | 7 | ALA2388096 | Rattus norvegicus | |||||
| 3. | ALA2387397 | 45 | Activity | > | 50 | % | ALA2388094 | % | Rattus norvegicus | |||
| 4. | ALA2387397 | 45 | solubility | >= | 200 | ug ml-1 | ALA2388091 | ug.mL-1 | ||||
| 5. | ALA2387397 | 45 | t1/2 | > | 12 | hr | ALA2388851 | hr | Rattus norvegicus | |||
| 6. | ALA2387397 | 45 | ED50 | = | 0.017 | mg kg-1 | ALA2388102 | mg.kg-1 | Mus musculus | |||
| 7. | ALA2387397 | 45 | IC50 | = | 0.2 | nM | ALA2388852 | 9.70 | nM | Rattus norvegicus | ||
| 8. | ALA2387397 | 45 | IC50 | = | 0.3 | nM | ALA2388853 | 9.52 | nM | Mus musculus | ||
| 9. | ALA2387397 | 45 | Cmax | = | 1 | ng/ml | ALA2388855 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA2387397 | 45 | IC50 | = | 4 | nM | ALA2388857 | 8.40 | nM | Homo sapiens | ||
| 11. | ALA2387397 | 45 | Papp | = | 27 | nm/s | ALA2388856 | nm/s | Canis lupus familiaris | |||
| 12. | ALA2387397 | 45 | Cmax | = | 27 | ng/ml | ALA2388854 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 13. | ALA2387397 | 45 | Drug recovery | = | 92 | % | ALA2388103 | % | ||||
| 14. | ALA2387397 | 45 | Efficacy | = | 98 | % | ALA2388101 | % | Mus musculus | |||
| 15. | ALA2387397 | 45 | Activity | 0 | ALA2388093 | Active | Rattus norvegicus | |||||
| 16. | ALA2387397 | 45 | Activity | 0 | ALA2388092 | Active | Rattus norvegicus | |||||
| 17. | ALA2387397 | 45 | Stability | 0 | ALA2388089 | Unstable | % |
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