| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2387692 | 25 | IC50 | = | 7 | nM | ALA3778970 | 8.15 | nM | Homo sapiens | ||
| 2. | ALA2387692 | 25 | t1/2 | = | 0.1 | hr | ALA3778972 | hr | Homo sapiens | |||
| 3. | ALA2387692 | 25 | IC50 | = | 7 | nM | ALA2390624 | 8.15 | nM | Homo sapiens | ||
| 4. | ALA2387692 | 25 | IC50 | = | 2400 | nM | ALA2390622 | 5.62 | nM | Homo sapiens | ||
| 5. | ALA2387692 | 25 | Papp | = | 13 | ucm/s | ALA2390619 | ucm/s | Homo sapiens | |||
| 6. | ALA2387692 | 25 | Papp | = | 17 | ucm/s | ALA2390620 | ucm/s | Homo sapiens | |||
| 7. | ALA2387692 | 25 | solubility | = | 0.003 | mg/ml | ALA2390616 | ug.mL-1 | ||||
| 8. | ALA2387692 | 25 | solubility | = | 0.95 | mg/ml | ALA2390617 | ug.mL-1 | ||||
| 9. | ALA2387692 | 25 | pKa | = | 4.2 | ALA2390618 | ||||||
| 10. | ALA2387692 | 25 | logD | = | 0.7 | ALA2390614 | ||||||
| 11. | ALA2387692 | 25 | PPB | = | 98.8 | % | ALA2390609 | % | Rattus norvegicus | |||
| 12. | ALA2387692 | 25 | PPB | > | 99.9 | % | ALA2390608 | % | Homo sapiens | |||
| 13. | ALA2387692 | 25 | AUC | = | 1955 | ng.hr/ml | ALA2390607 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA2387692 | 25 | CL | = | 8.5 | ml/min.kg | ALA2390455 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 15. | ALA2387692 | 25 | beta t1/2 | = | 4.8 | hr | ALA2390456 | hr | Rattus norvegicus | |||
| 16. | ALA2387692 | 25 | Vdss | = | 1.6 | L/Kg | ALA2390454 | L.kg-1 | Rattus norvegicus | |||
| 17. | ALA2387692 | 25 | F | = | 73 | % | ALA2390453 | % | Rattus norvegicus | |||
| 18. | ALA2387692 | 25 | INH | < | 40 | % | ALA2390450 | % | Homo sapiens | |||
| 19. | ALA2387692 | 25 | INH | < | 40 | % | ALA2390449 | % | Homo sapiens | |||
| 20. | ALA2387692 | 25 | t1/2 | = | 12 | min | ALA2390447 | hr | Homo sapiens |
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