# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2392692 | 27, GSK2188931B | IC50 | = | 0.5 | nM | ALA4349280 | 9.30 | nM | Homo sapiens | ||
2. | ALA2392692 | 27, GSK2188931B | IC50 | = | 0.5 | nM | ALA2393704 | 9.30 | nM | Homo sapiens | ||
3. | ALA2392692 | 27, GSK2188931B | IC50 | = | 3 | nM | ALA2393705 | 8.52 | nM | Homo sapiens | ||
4. | ALA2392692 | 27, GSK2188931B | CL | = | 12 | ml/min.kg | ALA2393703 | mL.min-1.kg-1 | Rattus norvegicus | |||
5. | ALA2392692 | 27, GSK2188931B | IC50 | > | 33000 | nM | ALA2393701 | nM | Homo sapiens | |||
6. | ALA2392692 | 27, GSK2188931B | IC50 | = | 2 | nM | ALA2393702 | 8.70 | nM | Rattus norvegicus | ||
7. | ALA2392692 | 27, GSK2188931B | Fu | = | 1.5 | % | ALA2393700 | Rattus norvegicus | ||||
8. | ALA2392692 | 27, GSK2188931B | IC50 | > | 50 | uM | ALA2393699 | nM | Homo sapiens | |||
9. | ALA2392692 | 27, GSK2188931B | CL | = | 12 | ml/min.kg | ALA2393698 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA2392692 | 27, GSK2188931B | t1/2 | = | 4.6 | hr | ALA2393697 | hr | Rattus norvegicus | |||
11. | ALA2392692 | 27, GSK2188931B | Vdss | = | 2.1 | L/Kg | ALA2393695 | L.kg-1 | Rattus norvegicus | |||
12. | ALA2392692 | 27, GSK2188931B | AUC/dose | = | 1.3 | hr.Kg/L | ALA2393696 | hr.Kg/L | Rattus norvegicus | |||
13. | ALA2392692 | 27, GSK2188931B | F | = | 100 | % | ALA2393694 | % | Rattus norvegicus | |||
14. | ALA2392692 | 27, GSK2188931B | IC50 | > | 30 | uM | ALA2396470 | nM | Homo sapiens | |||
15. | ALA2392692 | 27, GSK2188931B | IC50 | > | 10 | uM | ALA2396468 | nM | Homo sapiens | |||
16. | ALA2392692 | 27, GSK2188931B | IC50 | > | 10 | uM | ALA2396469 | nM | Homo sapiens | |||
17. | ALA2392692 | 27, GSK2188931B | IC50 | > | 10 | uM | ALA2396467 | nM | Homo sapiens | |||
18. | ALA2392692 | 27, GSK2188931B | INH | = | 50 | % | ALA2395880 | % | Rattus norvegicus | |||
19. | ALA2392692 | 27, GSK2188931B | Cmax | = | 16 | nM | ALA2395878 | nM | Rattus norvegicus | |||
20. | ALA2392692 | 27, GSK2188931B | Cmax | = | 223 | nM | ALA2395879 | nM | Rattus norvegicus |