# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2396674 | 9, MI-888 | Ki | = | 0.44 | nM | ALA5232244 | 9.36 | nM | Homo sapiens | ||
2. | ALA2396674 | 9, MI-888 | Activity | > | 10 | % | ALA3380272 | % | ||||
3. | ALA2396674 | 9, MI-888 | Activity | = | 2 | % | ALA3380271 | % | ||||
4. | ALA2396674 | 9, MI-888 | Activity | = | 2 | % | ALA3380270 | % | ||||
5. | ALA2396674 | 9, MI-888 | Stability | = | 97.7 | % | ALA3380267 | % | ||||
6. | ALA2396674 | 9, MI-888 | Stability | = | 98.6 | % | ALA3380266 | % | ||||
7. | ALA2396674 | 9, MI-888 | Stability | = | 99.56 | % | ALA3380265 | % | ||||
8. | ALA2396674 | 9, MI-888 | Stability | = | 100 | % | ALA3380264 | % | ||||
9. | ALA2396674 | 9, MI-888 | IC50 | = | 6.8 | nM | ALA3223537 | 8.17 | nM | Homo sapiens | ||
10. | ALA2396674 | 9, MI-888 | IC50 | < | 100 | nM | ALA3705834 | 314274 | nM | Homo sapiens | ||
11. | ALA2396674 | 9, MI-888 | IC50 | = | 5.6 | nM | ALA3705138 | 8.25 | 246807 | nM | Homo sapiens | |
12. | ALA2396674 | 9, MI-888 | IC50 | = | 6.8 | nM | ALA2401075 | 8.17 | nM | Homo sapiens | ||
13. | ALA2396674 | 9, MI-888 | Ki | = | 0.44 | nM | ALA2401074 | 9.36 | nM | Homo sapiens | ||
14. | ALA2396674 | 9, MI-888 | IC50 | = | 0.08 | uM | ALA2401073 | 7.10 | nM | Homo sapiens | ||
15. | ALA2396674 | 9, MI-888 | IC50 | = | 0.06 | uM | ALA2401072 | 7.22 | nM | |||
16. | ALA2396674 | 9, MI-888 | t1/2 | > | 60 | min | ALA2401071 | hr | Mus musculus | |||
17. | ALA2396674 | 9, MI-888 | t1/2 | > | 60 | min | ALA2401070 | hr | Rattus norvegicus | |||
18. | ALA2396674 | 9, MI-888 | t1/2 | > | 60 | min | ALA2401069 | hr | Homo sapiens | |||
19. | ALA2396674 | 9, MI-888 | Cmax | = | 1726 | ug/L | ALA2401068 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
20. | ALA2396674 | 9, MI-888 | AUCt | = | 14874 | ug/L/h | ALA2401067 | ng.hr.mL-1 | Rattus norvegicus |