# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2407757 | 12ax | t1/2 | = | 0.5 | hr | ALA2410655 | hr | Mus musculus | |||
2. | ALA2407757 | 12ax | Cmax | = | 1.6 | uM | ALA2410653 | nM | Mus musculus | |||
3. | ALA2407757 | 12ax | Vdss | = | 2.5 | L/Kg | ALA2410652 | L.kg-1 | Mus musculus | |||
4. | ALA2407757 | 12ax | F | = | 11 | % | ALA2410650 | % | Mus musculus | |||
5. | ALA2407757 | 12ax | CL | = | 128 | ml/min.kg | ALA2410656 | mL.min-1.kg-1 | Mus musculus | |||
6. | ALA2407757 | 12ax | AUC | = | 261 | ng.hr/ml | ALA2410654 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA2407757 | 12ax | AUC | = | 285 | ng.hr/ml | ALA2410651 | ng.hr.mL-1 | Mus musculus | |||
8. | ALA2407757 | 12ax | IC50 | = | 0.023 | uM | ALA2412856 | 7.64 | nM | Homo sapiens | ||
9. | ALA2407757 | 12ax | IC50 | = | 0.044 | uM | ALA2412855 | 7.36 | nM | Homo sapiens | ||
10. | ALA2407757 | 12ax | t1/2 | = | 0.5 | hr | ALA2412851 | hr | Mus musculus | |||
11. | ALA2407757 | 12ax | ERH | = | 0.73 | ALA2412854 | Homo sapiens | |||||
12. | ALA2407757 | 12ax | ERH | = | 0.84 | ALA2412853 | Mus musculus | |||||
13. | ALA2407757 | 12ax | Cmax | = | 1.6 | uM | ALA2412849 | nM | Mus musculus | |||
14. | ALA2407757 | 12ax | Vdss | = | 2.5 | L/Kg | ALA2412848 | L.kg-1 | Mus musculus | |||
15. | ALA2407757 | 12ax | F | = | 11 | % | ALA2412665 | % | Mus musculus | |||
16. | ALA2407757 | 12ax | CL | = | 128 | ml/min.kg | ALA2412850 | mL.min-1.kg-1 | Mus musculus | |||
17. | ALA2407757 | 12ax | AUC | = | 261 | ng.hr/ml | ALA2412852 | ng.hr.mL-1 | Mus musculus | |||
18. | ALA2407757 | 12ax | AUC | = | 285 | ng.hr/ml | ALA2412664 | ng.hr.mL-1 | Mus musculus |