| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2414265 | 20 | IC50 | = | 10.66 | nM | ALA2415452 | 7.97 | nM | Plasmodium falciparum | ||
| 2. | ALA2414265 | 20 | IC50 | = | 142.9 | nM | ALA2415451 | 6.84 | nM | Plasmodium falciparum | ||
| 3. | ALA2414265 | 20 | Ratio CC50/IC50 | = | 4616.14 | ALA2415450 | ||||||
| 4. | ALA2414265 | 20 | Ratio IC50 | = | 13.4 | ALA2415449 | Plasmodium falciparum | |||||
| 5. | ALA2414265 | 20 | IC50 | = | 5.29 | ug ml-1 | ALA2415448 | ug.mL-1 | Mus musculus | |||
| 6. | ALA2414265 | 20 | INH | 0 | ALA2415448 | Dose-dependent effect | % | Mus musculus | ||||
| 7. | ALA2414265 | 20 | Activity | = | 99.99 | % | ALA2415447 | % | Plasmodium yoelii | |||
| 8. | ALA2414265 | 20 | Activity | = | 99.99 | % | ALA2415446 | % | Plasmodium yoelii | |||
| 9. | ALA2414265 | 20 | Activity | = | 60 | % | ALA2415302 | % | Plasmodium yoelii | |||
| 10. | ALA2414265 | 20 | Activity | = | 60 | % | ALA2415301 | % | Plasmodium yoelii | |||
| 11. | ALA2414265 | 20 | Activity | = | 60 | % | ALA2415300 | % | Plasmodium yoelii | |||
| 12. | ALA2414265 | 20 | Cmax | = | 49.2 | ng/ml | ALA2415296 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 13. | ALA2414265 | 20 | Tmax | = | 2 | hr | ALA2415295 | hr | Rattus norvegicus | |||
| 14. | ALA2414265 | 20 | AUCt | = | 593.3 | ng.hr/ml | ALA2415292 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA2414265 | 20 | beta t1/2 | = | 5.27 | hr | ALA2415290 | hr | Rattus norvegicus | |||
| 16. | ALA2414265 | 20 | Vd | = | 28.16 | l | ALA2415288 | l | Rattus norvegicus | |||
| 17. | ALA2414265 | 20 | CL | = | 3.7 | L/hr | ALA2415286 | L/hr | Rattus norvegicus | |||
| 18. | ALA2414265 | 20 | MST | = | 23.6 | day | ALA2415284 | day | Plasmodium yoelii | |||
| 19. | ALA2414265 | 20 | MST | = | 25.2 | day | ALA2415283 | day | Plasmodium yoelii | |||
| 20. | ALA2414265 | 20 | Activity | = | 60 | % | ALA2415282 | % | Plasmodium yoelii |
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