# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2414617 | 2g, TA-3404 | IC50 | = | 2 | nM | ALA2415852 | 8.70 | nM | Homo sapiens | ||
2. | ALA2414617 | 2g, TA-3404 | IC50 | = | 750 | nM | ALA2415851 | 6.12 | nM | Homo sapiens | ||
3. | ALA2414617 | 2g, TA-3404 | INH | = | 19 | % | ALA2415850 | % | Rattus norvegicus | |||
4. | ALA2414617 | 2g, TA-3404 | Activity | = | 2666 | mg/day | ALA2415849 | mg/day | Rattus norvegicus | |||
5. | ALA2414617 | 2g, TA-3404 | Cmax | = | 964 | ng/ml | ALA2415848 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
6. | ALA2414617 | 2g, TA-3404 | AUC | = | 11371 | ng.hr/ml | ALA2415847 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA2414617 | 2g, TA-3404 | AUC | = | 10391 | ng.hr/ml | ALA2415846 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA2414617 | 2g, TA-3404 | t1/2 | = | 3.22 | hr | ALA2415845 | hr | Rattus norvegicus | |||
9. | ALA2414617 | 2g, TA-3404 | t1/2 | = | 3.53 | hr | ALA2415844 | hr | Rattus norvegicus | |||
10. | ALA2414617 | 2g, TA-3404 | CL | = | 264 | ml/hr/kg | ALA2415843 | mL.min-1.kg-1 | Rattus norvegicus | |||
11. | ALA2414617 | 2g, TA-3404 | Vdss | = | 1000 | ml/kg | ALA2415842 | L.kg-1 | Rattus norvegicus | |||
12. | ALA2414617 | 2g, TA-3404 | F | = | 27.4 | % | ALA2415841 | % | Rattus norvegicus | |||
13. | ALA2414617 | 2g, TA-3404 | Activity | = | 43 | % | ALA2415840 | % | Mus musculus | |||
14. | ALA2414617 | 2g, TA-3404 | Activity | 0 | ALA2415839 | Non-toxic | Mus musculus | |||||
15. | ALA2414617 | 2g, TA-3404 | IC50 | = | 2 | nM | ALA5129922 | 8.70 | nM | Homo sapiens |