| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2414670 | 52 | Activity | 0 | ALA2415189 | Active | Mus musculus | |||||
| 2. | ALA2414670 | 52 | Fu | = | 0.09 | ALA2415186 | Mus musculus | |||||
| 3. | ALA2414670 | 52 | Vdss | = | 1.2 | L/Kg | ALA2415504 | L.kg-1 | Rattus norvegicus | |||
| 4. | ALA2414670 | 52 | FC | = | 1.3 | ALA2415198 | Rattus norvegicus | |||||
| 5. | ALA2414670 | 52 | FC | = | 1.5 | ALA2415197 | Rattus norvegicus | |||||
| 6. | ALA2414670 | 52 | FC | = | 1.5 | ALA2415194 | Rattus norvegicus | |||||
| 7. | ALA2414670 | 52 | logD | = | 2.3 | ALA2415209 | ||||||
| 8. | ALA2414670 | 52 | t1/2 | = | 2.7 | hr | ALA2415502 | hr | Rattus norvegicus | |||
| 9. | ALA2414670 | 52 | CL | = | 5.3 | ml/min.kg | ALA2415506 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 10. | ALA2414670 | 52 | IC50 | > | 10 | uM | ALA2415208 | nM | Homo sapiens | |||
| 11. | ALA2414670 | 52 | IC50 | = | 23 | nM | ALA2415509 | 7.64 | nM | Homo sapiens | ||
| 12. | ALA2414670 | 52 | INH | = | 23 | % | ALA2415207 | % | Homo sapiens | |||
| 13. | ALA2414670 | 52 | IC50 | > | 30 | uM | ALA2415206 | nM | Homo sapiens | |||
| 14. | ALA2414670 | 52 | IC50 | > | 30 | uM | ALA2415177 | nM | Homo sapiens | |||
| 15. | ALA2414670 | 52 | Papp | = | 39 | ucm/s | ALA2415507 | ucm/s | ||||
| 16. | ALA2414670 | 52 | F | = | 53 | % | ALA2415503 | % | Rattus norvegicus | |||
| 17. | ALA2414670 | 52 | IC50 | = | 60 | nM | ALA2415510 | 7.22 | nM | Homo sapiens | ||
| 18. | ALA2414670 | 52 | Cmax | = | 118 | ng/ml | ALA2415191 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 19. | ALA2414670 | 52 | AUC | = | 727 | ng.hr/ml | ALA2415505 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA2414670 | 52 | CLH(app) | = | 8 | ml/min.kg | ALA2415508 | mL.min-1.kg-1 | Homo sapiens |
The page will load shortly, Thanks for your patience!