# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2418831 | 11d | F | = | 0.25 | % | ALA2422308 | % | Rattus norvegicus | |||
2. | ALA2418831 | 11d | MRT | = | 0.912 | hr | ALA2422307 | hr | Rattus norvegicus | |||
3. | ALA2418831 | 11d | Vdss | = | 0.918 | L/Kg | ALA2422310 | L.kg-1 | Rattus norvegicus | |||
4. | ALA2418831 | 11d | AUCt | = | 0.951 | kg.hr/L | ALA2422314 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA2418831 | 11d | AUC | = | 0.994 | kg.hr/L | ALA2422313 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA2418831 | 11d | t1/2 | = | 3.12 | hr | ALA2422312 | hr | Rattus norvegicus | |||
7. | ALA2418831 | 11d | C0 | = | 4.77 | mg/L | ALA2422311 | mg/L | Rattus norvegicus | |||
8. | ALA2418831 | 11d | CL | = | 16.8 | ml/min.Kg | ALA2422309 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA2418831 | 11d | IC50 | = | 21 | nM | ALA2423684 | 7.68 | nM | Homo sapiens | ||
10. | ALA2418831 | 11d | IC50 | = | 23 | nM | ALA2423683 | 7.64 | nM | Homo sapiens | ||
11. | ALA2418831 | 11d | F | > | 50 | % | ALA2422306 | % | Rattus norvegicus | |||
12. | ALA2418831 | 11d | logD | = | 2.4 | ALA2423682 |