# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2418996 | 2e | logD | = | 1.5 | ALA2423682 | ||||||
2. | ALA2418996 | 2e | Vdss | = | 1.51 | L/Kg | ALA2422310 | L.kg-1 | Rattus norvegicus | |||
3. | ALA2418996 | 2e | AUCt | = | 2.05 | kg.hr/L | ALA2422314 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA2418996 | 2e | AUC | = | 2.12 | kg.hr/L | ALA2422313 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA2418996 | 2e | MRT | = | 2.14 | hr | ALA2422307 | hr | Rattus norvegicus | |||
6. | ALA2418996 | 2e | C0 | = | 4.72 | mg/L | ALA2422311 | mg/L | Rattus norvegicus | |||
7. | ALA2418996 | 2e | F | = | 4.8 | % | ALA2422308 | % | Rattus norvegicus | |||
8. | ALA2418996 | 2e | t1/2 | = | 7.83 | hr | ALA2422312 | hr | Rattus norvegicus | |||
9. | ALA2418996 | 2e | CL | = | 7.87 | ml/min.Kg | ALA2422309 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA2418996 | 2e | F | > | 50 | % | ALA2422306 | % | Rattus norvegicus | |||
11. | ALA2418996 | 2e | IC50 | = | 200 | nM | ALA2423684 | 6.70 | nM | Homo sapiens | ||
12. | ALA2418996 | 2e | IC50 | = | 290 | nM | ALA2423683 | 6.54 | nM | Homo sapiens |