# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2419501 | 13 | IC50 | = | 0.017 | uM | ALA2423149 | 7.77 | nM | Homo sapiens | ||
2. | ALA2419501 | 13 | IC50 | = | 0.033 | uM | ALA2423148 | 7.48 | nM | Homo sapiens | ||
3. | ALA2419501 | 13 | IC50 | = | 2.4 | uM | ALA2423147 | 5.62 | nM | Homo sapiens | ||
4. | ALA2419501 | 13 | logD | = | 2 | ALA2424028 | ||||||
5. | ALA2419501 | 13 | Kinetic_solubility | = | 120 | uM | ALA2424027 | nM | ||||
6. | ALA2419501 | 13 | permeability | = | 0.3 | ucm/s | ALA2424026 | ucm/s | Homo sapiens | |||
7. | ALA2419501 | 13 | CLH | < | 12 | microL/min/mg | ALA2424025 | mL.min-1.g-1 | Canis lupus familiaris | |||
8. | ALA2419501 | 13 | pKa | = | 3.6 | ALA2424024 | ||||||
9. | ALA2419501 | 13 | IC50 | > | 50 | uM | ALA2424023 | nM | Homo sapiens | |||
10. | ALA2419501 | 13 | IC50 | > | 50 | uM | ALA2424022 | nM | Homo sapiens | |||
11. | ALA2419501 | 13 | Fu | = | 1.9 | % | ALA2424021 | Canis lupus familiaris | ||||
12. | ALA2419501 | 13 | CL | = | 9.8 | ml/min.kg | ALA2424020 | mL.min-1.kg-1 | Canis lupus familiaris | |||
13. | ALA2419501 | 13 | ED50 | = | 10 | ug/Kg/min | ALA2424013 | ug/Kg/min | Canis lupus familiaris | |||
14. | ALA2419501 | 13 | ED50 | = | 10 | ug/Kg/min | ALA2423150 | ug/Kg/min | Canis lupus familiaris | |||
15. | ALA2419501 | 13 | MED | = | 100 | ug/Kg/min | ALA2424012 | ug/Kg/min | Canis lupus familiaris | |||
16. | ALA2419501 | 13 | TI | >= | 10 | ALA2424011 | ||||||
17. | ALA2419501 | 13 | F | = | 100 | % | ALA2424017 | % | Canis lupus familiaris | |||
18. | ALA2419501 | 13 | t1/2 | = | 3.1 | hr | ALA2424015 | hr | Canis lupus familiaris | |||
19. | ALA2419501 | 13 | Activity | 0 | ALA2424013 | Dose-dependent effect | Canis lupus familiaris | |||||
20. | ALA2419501 | 13 | INH | 0 | ALA2423150 | Dose-dependent effect | % | Canis lupus familiaris |