| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2419597 | 22 | IC50 | = | 4.2 | nM | ALA2422747 | 8.38 | nM | Homo sapiens | ||
| 2. | ALA2419597 | 22 | IC50 | = | 11 | nM | ALA2422748 | 7.96 | nM | Homo sapiens | ||
| 3. | ALA2419597 | 22 | logD | = | 2 | ALA2422746 | ||||||
| 4. | ALA2419597 | 22 | CLH | = | 12 | microL/min/mg | ALA2422745 | mL.min-1.g-1 | Homo sapiens | |||
| 5. | ALA2419597 | 22 | Papp | = | 9.7 | ucm/s | ALA2422744 | ucm/s | ||||
| 6. | ALA2419597 | 22 | INH | 0 | ALA2422742 | Not Active | % | Homo sapiens | ||||
| 7. | ALA2419597 | 22 | INH | 0 | ALA2422741 | Not Active | % | Homo sapiens | ||||
| 8. | ALA2419597 | 22 | INH | 0 | ALA2422740 | Not Active | % | Homo sapiens | ||||
| 9. | ALA2419597 | 22 | INH | 0 | ALA2422739 | Not Active | % | Homo sapiens | ||||
| 10. | ALA2419597 | 22 | INH | 0 | ALA2422738 | Not Active | % | Homo sapiens | ||||
| 11. | ALA2419597 | 22 | solubility | = | 0.13 | ug ml-1 | ALA2422737 | ug.mL-1 | ||||
| 12. | ALA2419597 | 22 | F | = | 28 | % | ALA2422542 | % | Rattus norvegicus | |||
| 13. | ALA2419597 | 22 | Cmax | = | 186 | ng/ml | ALA2422541 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 14. | ALA2419597 | 22 | AUClast | = | 713 | ng.hr/ml | ALA2422540 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA2419597 | 22 | CL | = | 41 | ml/min.Kg | ALA2422538 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 16. | ALA2419597 | 22 | IC50 | = | 2.6 | nM | ALA3706246 | 8.59 | 293680 | nM | Homo sapiens | |
| 17. | ALA2419597 | 22 | IC50 | = | 14 | nM | ALA3706245 | 7.85 | 293556 | nM | Homo sapiens |
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