# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2424928 | 1, GSK966587 | MIC90 | = | 0.125 | ug ml-1 | ALA4036607 | ug.mL-1 | Streptococcus pyogenes | |||
2. | ALA2424928 | 1, GSK966587 | MIC90 | = | 0.5 | ug ml-1 | ALA4036606 | ug.mL-1 | Staphylococcus aureus | |||
3. | ALA2424928 | 1, GSK966587 | MIC | = | 8 | ug ml-1 | ALA4036594 | ug.mL-1 | Staphylococcus aureus | |||
4. | ALA2424928 | 1, GSK966587 | IC50 | = | 4.96 | uM | ALA4036598 | 5.30 | nM | |||
5. | ALA2424928 | 1, GSK966587 | IC50 | = | 0.448 | uM | ALA4036599 | 6.35 | nM | |||
6. | ALA2424928 | 1, GSK966587 | IC50 | > | 300 | uM | ALA4036596 | nM | Homo sapiens | |||
7. | ALA2424928 | 1, GSK966587 | MIC | = | 4 | ug ml-1 | ALA4036597 | ug.mL-1 | Staphylococcus aureus | |||
8. | ALA2424928 | 1, GSK966587 | MIC | = | 0.125 | ug ml-1 | ALA4036600 | ug.mL-1 | Staphylococcus aureus | |||
9. | ALA2424928 | 1, GSK966587 | MIC | = | 0.31 | ug ml-1 | ALA4036601 | ug.mL-1 | Staphylococcus aureus | |||
10. | ALA2424928 | 1, GSK966587 | IC50 | = | 0.035 | ug ml-1 | ALA2427865 | ug.mL-1 | ||||
11. | ALA2424928 | 1, GSK966587 | MIC | = | 1 | ug ml-1 | ALA2427864 | ug.mL-1 | Haemophilus influenzae | |||
12. | ALA2424928 | 1, GSK966587 | MIC | = | 0.125 | ug ml-1 | ALA2427863 | ug.mL-1 | Staphylococcus aureus | |||
13. | ALA2424928 | 1, GSK966587 | MIC | = | 0.125 | ug ml-1 | ALA2427862 | ug.mL-1 | Streptococcus pneumoniae | |||
14. | ALA2424928 | 1, GSK966587 | IC50 | = | 239 | uM | ALA2427861 | nM | Homo sapiens | |||
15. | ALA2424928 | 1, GSK966587 | IC50 | = | 310 | uM | ALA2427860 | nM | Homo sapiens | |||
16. | ALA2424928 | 1, GSK966587 | CL | = | 62.2 | ml/min.kg | ALA2427859 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA2424928 | 1, GSK966587 | CL | = | 18.1 | ml/min.kg | ALA2427858 | mL.min-1.kg-1 | Canis lupus familiaris | |||
18. | ALA2424928 | 1, GSK966587 | CL | = | 25.1 | ml/min.kg | ALA2427857 | mL.min-1.kg-1 | Macaca fascicularis | |||
19. | ALA2424928 | 1, GSK966587 | Vdss | = | 8.6 | L/Kg | ALA2427856 | L.kg-1 | Rattus norvegicus | |||
20. | ALA2424928 | 1, GSK966587 | Vdss | = | 6.4 | L/Kg | ALA2427855 | L.kg-1 | Canis lupus familiaris |