Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA2426244	PQS	Activity	=	100	%	ALA2427493			%	Pseudomonas aeruginosa PA14
2.	ALA2426244	PQS	Kd	=	0.21	uM	ALA2428111	6.68		nM	Pseudomonas aeruginosa PA14
3.	ALA2426244	PQS	CC50	>	20	uM	ALA4296191		Median N= 2; Maxinhib 45.0 Pct	nM	Homo sapiens
4.	ALA2426244	PQS	HC10	>	20	uM	ALA4296784		Median N= 2; Maxinhib 0.8 Pct	uM
5.	ALA2426244	PQS	MIC	>	20	uM	ALA4296184		Median N= 2; Maxinhib 11.2 Pct	nM	Staphylococcus aureus
6.	ALA2426244	PQS	MIC	>	20	uM	ALA4296802		Median N= 2; Maxinhib 52.7 Pct	nM	Pseudomonas aeruginosa
7.	ALA2426244	PQS	MIC	>	20	uM	ALA4296188		Median N= 2; Maxinhib 24.8 Pct	nM	Acinetobacter baumannii
8.	ALA2426244	PQS	MIC	>	20	uM	ALA4296187		Median N= 2; Maxinhib 22.9 Pct	nM	Pseudomonas aeruginosa
9.	ALA2426244	PQS	MIC	>	20	uM	ALA4296186		Median N= 2; Maxinhib 26.3 Pct	nM	Klebsiella pneumoniae
10.	ALA2426244	PQS	MIC	>	20	uM	ALA4296185		Median N= 2; Maxinhib 29.8 Pct	nM	Escherichia coli
11.	ALA2426244	PQS	MIC	>	20	uM	ALA4296190		Median N= 2; Maxinhib 6.6 Pct	nM	Cryptococcus neoformans
12.	ALA2426244	PQS	MIC	>	20	uM	ALA4296189		Median N= 2; Maxinhib 8.8 Pct	nM	Candida albicans
13.	ALA2426244	PQS	INH		0		ALA4810777		Active	%
14.	ALA2426244	PQS	FC	=	0.98		ALA4810776
15.	ALA2426244	PQS	Activity		0		ALA4810775		Dose-Dependent Effect
16.	ALA2426244	PQS	Activity		0		ALA4810774		Active
17.	ALA2426244	PQS	Activity		0		ALA4810773		Not Active		Mus musculus
18.	ALA2426244	PQS	Activity		0		ALA4810772		Active		Mus musculus
19.	ALA2426244	PQS	Activity		0		ALA4810771		Active		Mus musculus
20.	ALA2426244	PQS	Activity	=	37.49	%	ALA4810770			%	Mus musculus