# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2435924 | 15a | EC50 | = | 35 | nM | ALA2439686 | 7.46 | nM | Homo sapiens | ||
2. | ALA2435924 | 15a | Activity | = | 101 | % | ALA2439684 | % | Homo sapiens | |||
3. | ALA2435924 | 15a | EC50 | = | 0.15 | uM | ALA2439681 | 6.82 | nM | Mus musculus | ||
4. | ALA2435924 | 15a | Activity | = | 121 | % | ALA2439680 | % | Mus musculus | |||
5. | ALA2435924 | 15a | Tmax | = | 1.9 | hr | ALA2439569 | hr | Rattus norvegicus | |||
6. | ALA2435924 | 15a | Cmax | = | 16.3 | ng/ml | ALA2439568 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA2435924 | 15a | AUCt | = | 49.1 | ng.hr/ml | ALA2439567 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA2435924 | 15a | AUC | = | 55 | ng.hr/ml | ALA2439566 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA2435924 | 15a | MRT | = | 2.6 | hr | ALA2439565 | hr | Rattus norvegicus | |||
10. | ALA2435924 | 15a | MRT | = | 3.6 | hr | ALA2439564 | hr | Rattus norvegicus | |||
11. | ALA2435924 | 15a | CL | = | 91.2 | L/hr/kg | ALA2439563 | mL.min-1.kg-1 | Rattus norvegicus | |||
12. | ALA2435924 | 15a | t1/2 | = | 2.3 | hr | ALA2439562 | hr | Rattus norvegicus | |||
13. | ALA2435924 | 15a | Activity | 0 | ALA2439682 | Not Active | Mus musculus | |||||
14. | ALA2435924 | 15a | Activity | 0 | ALA2439683 | Non-toxic | Mus musculus |